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Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo.
Hansen L, McMahon M, Turner HL, Zhu X, Turner JS, Ozorowski G, Stadlbauer D, Vahokoski J, Schmitz AJ, Rizk AA, Alsoussi WB, Strohmeier S, Yu W, Choreño-Parra JA, Jiménez-Alvarez L, Cruz-Lagunas A, Zúñiga J, Mudd PA, Cox RJ, Wilson IA, Ward AB, Ellebedy AH, Krammer F. Hansen L, et al. Among authors: alsoussi wb. Immunity. 2023 Aug 8;56(8):1927-1938.e8. doi: 10.1016/j.immuni.2023.07.004. Epub 2023 Jul 27. Immunity. 2023. PMID: 37506693
SARS-CoV-2 Omicron boosting induces de novo B cell response in humans.
Alsoussi WB, Malladi SK, Zhou JQ, Liu Z, Ying B, Kim W, Schmitz AJ, Lei T, Horvath SC, Sturtz AJ, McIntire KM, Evavold B, Han F, Scheaffer SM, Fox IF, Mirza SF, Parra-Rodriguez L, Nachbagauer R, Nestorova B, Chalkias S, Farnsworth CW, Klebert MK, Pusic I, Strnad BS, Middleton WD, Teefey SA, Whelan SPJ, Diamond MS, Paris R, O'Halloran JA, Presti RM, Turner JS, Ellebedy AH. Alsoussi WB, et al. Nature. 2023 May;617(7961):592-598. doi: 10.1038/s41586-023-06025-4. Epub 2023 Apr 3. Nature. 2023. PMID: 37011668
Persons with HIV Develop Spike-Specific Lymph Node Germinal Center Responses following SARS-CoV-2 Vaccination.
Quinn M, Parra-Rodriguez L, Alsoussi WB, Ayres C, Klebert MK, Liu C, Suessen T, Scheaffer SM, Middleton WD, Teefey SA, Powderly WG, Diamond MS, Presti RM, Ellebedy AH, Turner JS, O'Halloran JA, Mudd PA. Quinn M, et al. Among authors: alsoussi wb. J Immunol. 2023 Apr 1;210(7):947-958. doi: 10.4049/jimmunol.2200920. J Immunol. 2023. PMID: 36779802 Free PMC article.
SARS-CoV-2 Omicron boosting induces de novo B cell response in humans.
Alsoussi WB, Malladi SK, Zhou JQ, Liu Z, Ying B, Kim W, Schmitz AJ, Lei T, Horvath SC, Sturtz AJ, McIntire KM, Evavold B, Han F, Scheaffer SM, Fox IF, Parra-Rodriguez L, Nachbagauer R, Nestorova B, Chalkias S, Farnsworth CW, Klebert MK, Pusic I, Strnad BS, Middleton WD, Teefey SA, Whelan SPJ, Diamond MS, Paris R, O'Halloran JA, Presti RM, Turner JS, Ellebedy AH. Alsoussi WB, et al. bioRxiv [Preprint]. 2022 Sep 22:2022.09.22.509040. doi: 10.1101/2022.09.22.509040. bioRxiv. 2022. PMID: 36172127 Free PMC article. Updated. Preprint.
Germinal centre-driven maturation of B cell response to mRNA vaccination.
Kim W, Zhou JQ, Horvath SC, Schmitz AJ, Sturtz AJ, Lei T, Liu Z, Kalaidina E, Thapa M, Alsoussi WB, Haile A, Klebert MK, Suessen T, Parra-Rodriguez L, Mudd PA, Whelan SPJ, Middleton WD, Teefey SA, Pusic I, O'Halloran JA, Presti RM, Turner JS, Ellebedy AH. Kim W, et al. Among authors: alsoussi wb. Nature. 2022 Apr;604(7904):141-145. doi: 10.1038/s41586-022-04527-1. Epub 2022 Feb 15. Nature. 2022. PMID: 35168246 Free PMC article.
Germinal centre-driven maturation of B cell response to SARS-CoV-2 vaccination.
Kim W, Zhou JQ, Sturtz AJ, Horvath SC, Schmitz AJ, Lei T, Kalaidina E, Thapa M, Alsoussi WB, Haile A, Klebert MK, Suessen T, Parra-Rodriguez L, Mudd PA, Middleton WD, Teefey SA, Pusic I, O'Halloran JA, Presti RM, Turner JS, Ellebedy AH. Kim W, et al. Among authors: alsoussi wb. bioRxiv [Preprint]. 2021 Nov 2:2021.10.31.466651. doi: 10.1101/2021.10.31.466651. bioRxiv. 2021. PMID: 34751268 Free PMC article. Updated. Preprint.
A vaccine-induced public antibody protects against SARS-CoV-2 and emerging variants.
Schmitz AJ, Turner JS, Liu Z, Zhou JQ, Aziati ID, Chen RE, Joshi A, Bricker TL, Darling TL, Adelsberg DC, Altomare CG, Alsoussi WB, Case JB, VanBlargan LA, Lei T, Thapa M, Amanat F, Jeevan T, Fabrizio T, O'Halloran JA, Shi PY, Presti RM, Webby RJ, Krammer F, Whelan SPJ, Bajic G, Diamond MS, Boon ACM, Ellebedy AH. Schmitz AJ, et al. Among authors: alsoussi wb. Immunity. 2021 Sep 14;54(9):2159-2166.e6. doi: 10.1016/j.immuni.2021.08.013. Epub 2021 Aug 17. Immunity. 2021. PMID: 34464596 Free PMC article.
A public vaccine-induced human antibody protects against SARS-CoV-2 and emerging variants.
Schmitz AJ, Turner JS, Liu Z, Aziati ID, Chen RE, Joshi A, Bricker TL, Darling TL, Adelsberg DC, Alsoussi WB, Case JB, Lei T, Thapa M, Amanat F, O'Halloran JA, Shi PY, Presti RM, Krammer F, Bajic G, Whelan SPJ, Diamond MS, Boon ACM, Ellebedy AH. Schmitz AJ, et al. Among authors: alsoussi wb. bioRxiv [Preprint]. 2021 Mar 24:2021.03.24.436864. doi: 10.1101/2021.03.24.436864. bioRxiv. 2021. PMID: 33791696 Free PMC article. Updated. Preprint.
Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective.
Madsen A, Dai YN, McMahon M, Schmitz AJ, Turner JS, Tan J, Lei T, Alsoussi WB, Strohmeier S, Amor M, Mohammed BM, Mudd PA, Simon V, Cox RJ, Fremont DH, Krammer F, Ellebedy AH. Madsen A, et al. Among authors: alsoussi wb. Immunity. 2020 Oct 13;53(4):852-863.e7. doi: 10.1016/j.immuni.2020.08.015. Epub 2020 Sep 24. Immunity. 2020. PMID: 32976769 Free PMC article.
14 results