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Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models.
Prieto Huarcaya S, Drobny A, Marques ARA, Di Spiezio A, Dobert JP, Balta D, Werner C, Rizo T, Gallwitz L, Bub S, Stojkovska I, Belur NR, Fogh J, Mazzulli JR, Xiang W, Fulzele A, Dejung M, Sauer M, Winner B, Rose-John S, Arnold P, Saftig P, Zunke F. Prieto Huarcaya S, et al. Among authors: arnold p. Autophagy. 2022 May;18(5):1127-1151. doi: 10.1080/15548627.2022.2045534. Epub 2022 Apr 28. Autophagy. 2022. PMID: 35287553 Free PMC article.
Detection of neuron-derived pathological α-synuclein in blood.
Kluge A, Bunk J, Schaeffer E, Drobny A, Xiang W, Knacke H, Bub S, Lückstädt W, Arnold P, Lucius R, Berg D, Zunke F. Kluge A, et al. Among authors: arnold p. Brain. 2022 Sep 14;145(9):3058-3071. doi: 10.1093/brain/awac115. Brain. 2022. PMID: 35722765
DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colon.
Fazio A, Bordoni D, Kuiper JWP, Weber-Stiehl S, Stengel ST, Arnold P, Ellinghaus D, Ito G, Tran F, Messner B, Henning A, Bernardes JP, Häsler R, Luzius A, Imm S, Hinrichsen F, Franke A, Huber S, Nikolaus S, Aden K, Schreiber S, Sommer F, Natoli G, Mishra N, Rosenstiel P. Fazio A, et al. Among authors: arnold p. Nat Commun. 2022 Oct 21;13(1):6266. doi: 10.1038/s41467-022-33844-2. Nat Commun. 2022. PMID: 36271073 Free PMC article.
Proteolysis of CD44 at the cell surface controls a downstream protease network.
Wöhner B, Li W, Hey S, Drobny A, Werny L, Becker-Pauly C, Lucius R, Zunke F, Linder S, Arnold P. Wöhner B, et al. Among authors: arnold p. Front Mol Biosci. 2023 Feb 17;10:1026810. doi: 10.3389/fmolb.2023.1026810. eCollection 2023. Front Mol Biosci. 2023. PMID: 36876041 Free PMC article.
1,446 results