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Pre-existing immunity to influenza virus hemagglutinin stalk might drive selection for antibody-escape mutant viruses in a human challenge model.
Park JK, Xiao Y, Ramuta MD, Rosas LA, Fong S, Matthews AM, Freeman AD, Gouzoulis MA, Batchenkova NA, Yang X, Scherler K, Qi L, Reed S, Athota R, Czajkowski L, Han A, Morens DM, Walters KA, Memoli MJ, Kash JC, Taubenberger JK. Park JK, et al. Among authors: batchenkova na. Nat Med. 2020 Aug;26(8):1240-1246. doi: 10.1038/s41591-020-0937-x. Epub 2020 Jun 29. Nat Med. 2020. PMID: 32601336 Free PMC article.
An inactivated multivalent influenza A virus vaccine is broadly protective in mice and ferrets.
Park J, Fong Legaspi SL, Schwartzman LM, Gygli SM, Sheng ZM, Freeman AD, Matthews LM, Xiao Y, Ramuta MD, Batchenkova NA, Qi L, Rosas LA, Williams SL, Scherler K, Gouzoulis M, Bellayr I, Morens DM, Walters KA, Memoli MJ, Kash JC, Taubenberger JK. Park J, et al. Among authors: batchenkova na. Sci Transl Med. 2022 Jul 13;14(653):eabo2167. doi: 10.1126/scitranslmed.abo2167. Epub 2022 Jul 13. Sci Transl Med. 2022. PMID: 35857640 Free PMC article.