Gao F - Search Results

1

Tie2-FGFR1 Interaction Induces Adaptive PI3K Inhibitor Resistance by Upregulating Aurora A/PLK1/CDK1 Signaling in Glioblastoma.

Li X, Martinez-Ledesma E, Zhang C, Gao F, Zheng S, Ding J, Wu S, Nguyen N, Clifford SC, Wen PY, Ligon KL, Yung WKA, Koul D. Li X, et al. Among authors: gao f. Cancer Res. 2019 Oct 1;79(19):5088-5101. doi: 10.1158/0008-5472.CAN-19-0325. Epub 2019 Aug 15. Cancer Res. 2019. PMID: 31416846

2

Wild-type TP53 defined gamma-secretase inhibitor sensitivity and synergistic activity with doxorubicin in GSCs.

Zhang C, Martinez-Ledesma E, Gao F, Zhang W, Ding J, Wu S, Li X, Wu J, Yuan Y, Koul D, Alfred Yung WK. Zhang C, et al. Among authors: gao f. Am J Cancer Res. 2019 Aug 1;9(8):1734-1745. eCollection 2019. Am J Cancer Res. 2019. PMID: 31497354 Free PMC article.

3

BRCA1 identified as a modulator of temozolomide resistance in P53 wild-type GBM using a high-throughput shRNA-based synthetic lethality screening.

Ding J, Wu S, Zhang C, Garyali A, Martinez-Ledesma E, Gao F, Pokkulandra A, Li X, Bristow C, Carugo A, Koul D, Yung WA. Ding J, et al. Among authors: gao f. Am J Cancer Res. 2019 Nov 1;9(11):2428-2441. eCollection 2019. Am J Cancer Res. 2019. PMID: 31815044 Free PMC article.

4

EGFR Amplification Induces Increased DNA Damage Response and Renders Selective Sensitivity to Talazoparib (PARP Inhibitor) in Glioblastoma.

Wu S, Gao F, Zheng S, Zhang C, Martinez-Ledesma E, Ezhilarasan R, Ding J, Li X, Feng N, Multani A, Sulman EP, Verhaak RG, de Groot JF, Heffernan TP, Yung WKA, Koul D. Wu S, et al. Among authors: gao f. Clin Cancer Res. 2020 Mar 15;26(6):1395-1407. doi: 10.1158/1078-0432.CCR-19-2549. Epub 2019 Dec 18. Clin Cancer Res. 2020. PMID: 31852834

5

Activation of WEE1 confers resistance to PI3K inhibition in glioblastoma.

Wu S, Wang S, Gao F, Li L, Zheng S, Yung WKA, Koul D. Wu S, et al. Among authors: gao f. Neuro Oncol. 2018 Jan 10;20(1):78-91. doi: 10.1093/neuonc/nox128. Neuro Oncol. 2018. PMID: 29016926 Free PMC article.

6

PARP-mediated PARylation of MGMT is critical to promote repair of temozolomide-induced O6-methylguanine DNA damage in glioblastoma.

Wu S, Li X, Gao F, de Groot JF, Koul D, Yung WKA. Wu S, et al. Among authors: gao f. Neuro Oncol. 2021 Jun 1;23(6):920-931. doi: 10.1093/neuonc/noab003. Neuro Oncol. 2021. PMID: 33433610 Free PMC article.

7

EGFR suppresses p53 function by promoting p53 binding to DNA-PKcs: a noncanonical regulatory axis between EGFR and wild-type p53 in glioblastoma.

Ding J, Li X, Khan S, Zhang C, Gao F, Sen S, Wasylishen AR, Zhao Y, Lozano G, Koul D, Alfred Yung WK. Ding J, et al. Among authors: gao f. Neuro Oncol. 2022 Oct 3;24(10):1712-1725. doi: 10.1093/neuonc/noac105. Neuro Oncol. 2022. PMID: 35474131 Free PMC article.

8

Preclinical therapeutic efficacy of a novel blood-brain barrier-penetrant dual PI3K/mTOR inhibitor with preferential response in PI3K/PTEN mutant glioma.

Koul D, Wang S, Wu S, Saito N, Zheng S, Gao F, Kaul I, Setoguchi M, Nakayama K, Koyama K, Shiose Y, Sulman EP, Hirota Y, Yung WKA. Koul D, et al. Among authors: gao f. Oncotarget. 2017 Mar 28;8(13):21741-21753. doi: 10.18632/oncotarget.15566. Oncotarget. 2017. PMID: 28423515 Free PMC article.

9

Mass Spectrometry-Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers.

Mundt F, Rajput S, Li S, Ruggles KV, Mooradian AD, Mertins P, Gillette MA, Krug K, Guo Z, Hoog J, Erdmann-Gilmore P, Primeau T, Huang S, Edwards DP, Wang X, Wang X, Kawaler E, Mani DR, Clauser KR, Gao F, Luo J, Davies SR, Johnson GL, Huang KL, Yoon CJ, Ding L, Fenyö D, Ellis MJ, Townsend RR, Held JM, Carr SA, Ma CX. Mundt F, et al. Among authors: gao f. Cancer Res. 2018 May 15;78(10):2732-2746. doi: 10.1158/0008-5472.CAN-17-1990. Epub 2018 Feb 22. Cancer Res. 2018. PMID: 29472518 Free PMC article.

10

TGF-β mediates homing of bone marrow-derived human mesenchymal stem cells to glioma stem cells.

Shinojima N, Hossain A, Takezaki T, Fueyo J, Gumin J, Gao F, Nwajei F, Marini FC, Andreeff M, Kuratsu J, Lang FF. Shinojima N, et al. Among authors: gao f. Cancer Res. 2013 Apr 1;73(7):2333-44. doi: 10.1158/0008-5472.CAN-12-3086. Epub 2013 Jan 30. Cancer Res. 2013. PMID: 23365134 Free PMC article.

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