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MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8+ T Cell Responses.
Hope JL, Zhao M, Stairiker CJ, Kiernan CH, Carey AJ, Mueller YM, van Meurs M, Brouwers-Haspels I, Otero DC, Bae EA, Faso HA, Maas A, de Looper H, Fortina PM, Rigoutsos I, Bradley LM, Erkeland SJ, Katsikis PD. Hope JL, et al. Among authors: kiernan ch. J Immunol. 2022 Feb 1;208(3):603-617. doi: 10.4049/jimmunol.2000621. Epub 2022 Jan 12. J Immunol. 2022. PMID: 35022277 Free PMC article.
Rapid in vitro generation of bona fide exhausted CD8+ T cells is accompanied by Tcf7 promotor methylation.
Zhao M, Kiernan CH, Stairiker CJ, Hope JL, Leon LG, van Meurs M, Brouwers-Haspels I, Boers R, Boers J, Gribnau J, van IJcken WFJ, Bindels EM, Hoogenboezem RM, Erkeland SJ, Mueller YM, Katsikis PD. Zhao M, et al. Among authors: kiernan ch. PLoS Pathog. 2020 Jun 24;16(6):e1008555. doi: 10.1371/journal.ppat.1008555. eCollection 2020 Jun. PLoS Pathog. 2020. PMID: 32579593 Free PMC article.
Stratification of hospitalized COVID-19 patients into clinical severity progression groups by immuno-phenotyping and machine learning.
Mueller YM, Schrama TJ, Ruijten R, Schreurs MWJ, Grashof DGB, van de Werken HJG, Lasinio GJ, Álvarez-Sierra D, Kiernan CH, Castro Eiro MD, van Meurs M, Brouwers-Haspels I, Zhao M, Li L, de Wit H, Ouzounis CA, Wilmsen MEP, Alofs TM, Laport DA, van Wees T, Kraker G, Jaimes MC, Van Bockstael S, Hernández-González M, Rokx C, Rijnders BJA, Pujol-Borrell R, Katsikis PD. Mueller YM, et al. Among authors: kiernan ch. Nat Commun. 2022 Feb 17;13(1):915. doi: 10.1038/s41467-022-28621-0. Nat Commun. 2022. PMID: 35177626 Free PMC article.
Ibrutinib directly reduces CD8+T cell exhaustion independent of BTK.
Li L, Zhao M, Kiernan CH, Castro Eiro MD, van Meurs M, Brouwers-Haspels I, Wilmsen MEP, Grashof DGB, van de Werken HJG, Hendriks RW, Mueller YM, Katsikis PD. Li L, et al. Among authors: kiernan ch. Front Immunol. 2023 Sep 12;14:1201415. doi: 10.3389/fimmu.2023.1201415. eCollection 2023. Front Immunol. 2023. PMID: 37771591 Free PMC article.
TLR9 plus STING Agonist Adjuvant Combination Induces Potent Neopeptide T Cell Immunity and Improves Immune Checkpoint Blockade Efficacy in a Tumor Model.
Castro Eiro MD, Hioki K, Li L, Wilmsen MEP, Kiernan CH, Brouwers-Haspels I, van Meurs M, Zhao M, de Wit H, Grashof DGB, van de Werken HJG, Mueller YM, Schliehe C, Temizoz B, Kobiyama K, Ishii KJ, Katsikis PD. Castro Eiro MD, et al. Among authors: kiernan ch. J Immunol. 2024 Feb 1;212(3):455-465. doi: 10.4049/jimmunol.2300038. J Immunol. 2024. PMID: 38063488 Free PMC article.
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