Lavin MF - Search Results

1

Senataxin plays an essential role with DNA damage response proteins in meiotic recombination and gene silencing.

Becherel OJ, Yeo AJ, Stellati A, Heng EY, Luff J, Suraweera AM, Woods R, Fleming J, Carrie D, McKinney K, Xu X, Deng C, Lavin MF. Becherel OJ, et al. Among authors: lavin mf. PLoS Genet. 2013 Apr;9(4):e1003435. doi: 10.1371/journal.pgen.1003435. Epub 2013 Apr 11. PLoS Genet. 2013. PMID: 23593030 Free PMC article.

2

Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage.

Suraweera A, Becherel OJ, Chen P, Rundle N, Woods R, Nakamura J, Gatei M, Criscuolo C, Filla A, Chessa L, Fusser M, Epe B, Gueven N, Lavin MF. Suraweera A, et al. Among authors: lavin mf. J Cell Biol. 2007 Jun 18;177(6):969-79. doi: 10.1083/jcb.200701042. Epub 2007 Jun 11. J Cell Biol. 2007. PMID: 17562789 Free PMC article.

3

Functional role for senataxin, defective in ataxia oculomotor apraxia type 2, in transcriptional regulation.

Suraweera A, Lim Y, Woods R, Birrell GW, Nasim T, Becherel OJ, Lavin MF. Suraweera A, et al. Among authors: lavin mf. Hum Mol Genet. 2009 Sep 15;18(18):3384-96. doi: 10.1093/hmg/ddp278. Epub 2009 Jun 10. Hum Mol Genet. 2009. PMID: 19515850

4

R-loops in proliferating cells but not in the brain: implications for AOA2 and other autosomal recessive ataxias.

Yeo AJ, Becherel OJ, Luff JE, Cullen JK, Wongsurawat T, Jenjaroenpun P, Kuznetsov VA, McKinnon PJ, Lavin MF. Yeo AJ, et al. Among authors: lavin mf. PLoS One. 2014 Mar 17;9(3):e90219. doi: 10.1371/journal.pone.0090219. eCollection 2014. PLoS One. 2014. PMID: 24637776 Free PMC article.

5

Senataxin protects the genome: Implications for neurodegeneration and other abnormalities.

Lavin MF, Yeo AJ, Becherel OJ. Lavin MF, et al. Rare Dis. 2013 Jun 6;1:e25230. doi: 10.4161/rdis.25230. eCollection 2013. Rare Dis. 2013. PMID: 25003001 Free PMC article.

6

Senataxin controls meiotic silencing through ATR activation and chromatin remodeling.

Yeo AJ, Becherel OJ, Luff JE, Graham ME, Richard D, Lavin MF. Yeo AJ, et al. Among authors: lavin mf. Cell Discov. 2015 Sep 29;1:15025. doi: 10.1038/celldisc.2015.25. eCollection 2015. Cell Discov. 2015. PMID: 27462424 Free PMC article.

7

Oocytes mount a noncanonical DNA damage response involving APC-Cdh1-mediated proteolysis.

Subramanian GN, Greaney J, Wei Z, Becherel O, Lavin M, Homer HA. Subramanian GN, et al. J Cell Biol. 2020 Apr 6;219(4):e201907213. doi: 10.1083/jcb.201907213. J Cell Biol. 2020. PMID: 32328643 Free PMC article.

8

Nucleolar localization of aprataxin is dependent on interaction with nucleolin and on active ribosomal DNA transcription.

Becherel OJ, Gueven N, Birrell GW, Schreiber V, Suraweera A, Jakob B, Taucher-Scholz G, Lavin MF. Becherel OJ, et al. Among authors: lavin mf. Hum Mol Genet. 2006 Jul 15;15(14):2239-49. doi: 10.1093/hmg/ddl149. Epub 2006 Jun 15. Hum Mol Genet. 2006. PMID: 16777843

9

Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage.

Harris JL, Jakob B, Taucher-Scholz G, Dianov GL, Becherel OJ, Lavin MF. Harris JL, et al. Among authors: lavin mf. Hum Mol Genet. 2009 Nov 1;18(21):4102-17. doi: 10.1093/hmg/ddp359. Epub 2009 Jul 30. Hum Mol Genet. 2009. PMID: 19643912

10

Mutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2.

Fogel BL, Cho E, Wahnich A, Gao F, Becherel OJ, Wang X, Fike F, Chen L, Criscuolo C, De Michele G, Filla A, Collins A, Hahn AF, Gatti RA, Konopka G, Perlman S, Lavin MF, Geschwind DH, Coppola G. Fogel BL, et al. Among authors: lavin mf. Hum Mol Genet. 2014 Sep 15;23(18):4758-69. doi: 10.1093/hmg/ddu190. Epub 2014 Apr 23. Hum Mol Genet. 2014. PMID: 24760770 Free PMC article.

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