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The World Health Organization's public health intelligence activities during the COVID-19 pandemic response, December 2019 to December 2021.
Togami E, Griffith B, Mahran M, Nezu IH, Mirembe BB, Kaasik-Aaslav K, Alexandrova-Ezerska L, Babu A, Sedai TR, Kato M, Abbas H, Sadek M, Nabeth P, MacDonald LE, Hernández-García L, Pires J, Ildefonso S, Stephen M, Lee TM, Impouma B, Matsui T, Moon S, Phenxay M, Biaukula V, Ochirpurev A, Schnitzler J, Fontaine J, Djordjevic I, Brindle H, Kolmer J, McMenamin M, Peron E, Kassamali Z, Greene-Cramer B, Hamblion E, Abdelmalik P, Pavlin BI, Mahamud AR, Morgan O. Togami E, et al. Among authors: macdonald le. Euro Surveill. 2022 Dec;27(49):2200142. doi: 10.2807/1560-7917.ES.2022.27.49.2200142. Euro Surveill. 2022. PMID: 36695442 Free PMC article.
WHO Global Situational Alert System: a mixed methods multistage approach to identify country-level COVID-19 alerts.
McMenamin M, Kolmer J, Djordjevic I, Campbell F, Laurenson-Schafer H, Abbate JL, Abdelgawad BM, Babu A, Balde T, Batra N, Bélorgeot VD, Brindle H, Dorji T, Esmail M, Hammermeister Nezu I, Hernández-García L, Hassan M, Idoko F, Karmin S, Kassamali ZA, Kato M, Matsui T, Duan M, Motaze V, Ogundiran O, Pavlin BI, Riviere-Cinnamond A, Ryan K, Schmidt T, Sedai T, Van Kerkhove MD, Zakaria T, Höhle M, Mahamud AR, le Polain de Waroux O; WHO Global Situational Alert System Group. McMenamin M, et al. BMJ Glob Health. 2023 Jul;8(7):e012241. doi: 10.1136/bmjgh-2023-012241. BMJ Glob Health. 2023. PMID: 37495371 Free PMC article.
Disseminating information on acute public health events globally: experiences from the WHO's Disease Outbreak News.
Lata H, Saad Duque NJ, Togami E, Miglietta A, Perkins D, Corpuz A, Kato M, Babu A, Dorji T, Matsui T, Almiron M, Cheng KY, MacDonald LE, Pukkila JT, Williams GS, Andraghetti R, Dolea C, Mahamud A, Morgan O, Olowokure B, Fall IS, Awofisayo-Okuyelu A, Hamblion E. Lata H, et al. Among authors: macdonald le. BMJ Glob Health. 2024 Feb 26;9(2):e012876. doi: 10.1136/bmjgh-2023-012876. BMJ Glob Health. 2024. PMID: 38413101 Free PMC article.
Monoclonal antibodies against GFRα3 are efficacious against evoked hyperalgesic and allodynic responses in mouse join pain models but, one of these, REGN5069, was not effective against pain in a randomized, placebo-controlled clinical trial in patients with osteoarthritis pain.
Somersan-Karakaya S, Turner KC, Cortes-Burgos L, Miller J, LaCroix-Fralish M, Logovinsky V, Patel Y, Torres R, Ganguly S, Breazna A, DeVeaux M, Bhore R, Gao M, Delfino FJ, Rafique A, Fairhurst JL, Hunt C, Babb R, Badithe A, Poueymirou WT, Surowitz R, Rottey S, Murphy AJ, Harari O, Macdonald LE, Croll SD. Somersan-Karakaya S, et al. Among authors: macdonald le. Neurobiol Pain. 2023 Jun 26;14:100136. doi: 10.1016/j.ynpai.2023.100136. eCollection 2023 Aug-Dec. Neurobiol Pain. 2023. PMID: 38099276 Free PMC article.
Crown-of-thorns starfish spines secrete defence proteins.
Hillberg AK, Smith MK, Lausen BS, Suwansa-Ard S, Johnston R, Mitu SA, MacDonald LE, Zhao M, Motti CA, Wang T, Elizur A, Nakashima K, Satoh N, Cummins SF. Hillberg AK, et al. Among authors: macdonald le. PeerJ. 2023 Aug 21;11:e15689. doi: 10.7717/peerj.15689. eCollection 2023. PeerJ. 2023. PMID: 37637177 Free PMC article.
IL-6-GP130 signaling protects human hepatocytes against lipid droplet accumulation in humanized liver models.
Carbonaro M, Wang K, Huang H, Frleta D, Patel A, Pennington A, Desclaux M, Moller-Tank S, Grindley J, Altarejos J, Zhong J, Polites G, Poueymirou W, Jaspers S, Kyratsous C, Zambrowicz B, Murphy A, Lin JC, Macdonald LE, Daly C, Sleeman M, Thurston G, Li Z. Carbonaro M, et al. Among authors: macdonald le. Sci Adv. 2023 Apr 14;9(15):eadf4490. doi: 10.1126/sciadv.adf4490. Epub 2023 Apr 14. Sci Adv. 2023. PMID: 37058568 Free PMC article.
Disruption of nuclear envelope integrity as a possible initiating event in tauopathies.
Prissette M, Fury W, Koss M, Racioppi C, Fedorova D, Dragileva E, Clarke G, Pohl T, Dugan J, Ahrens D, Chiu J, Hunt C, Siao CJ, Young T, Bhowmick A, Rogulin V, Desclaux M, Hayden EY, Podgorski M, Gao M, Macdonald LE, Frendewey D, Yancopoulos GD, Zambrowicz B. Prissette M, et al. Among authors: macdonald le. Cell Rep. 2022 Aug 23;40(8):111249. doi: 10.1016/j.celrep.2022.111249. Cell Rep. 2022. PMID: 36001963 Free article.
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