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Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans.
Sazzini M, Abondio P, Sarno S, Gnecchi-Ruscone GA, Ragno M, Giuliani C, De Fanti S, Ojeda-Granados C, Boattini A, Marquis J, Valsesia A, Carayol J, Raymond F, Pirazzini C, Marasco E, Ferrarini A, Xumerle L, Collino S, Mari D, Arosio B, Monti D, Passarino G, D'Aquila P, Pettener D, Luiselli D, Castellani G, Delledonne M, Descombes P, Franceschi C, Garagnani P. Sazzini M, et al. Among authors: Passarino G. BMC Biol. 2020 May 22;18(1):51. doi: 10.1186/s12915-020-00778-4. BMC Biol. 2020. PMID: 32438927 Free PMC article.
Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans.
De Benedictis G, Rose G, Carrieri G, De Luca M, Falcone E, Passarino G, Bonafe M, Monti D, Baggio G, Bertolini S, Mari D, Mattace R, Franceschi C. De Benedictis G, et al. FASEB J. 1999 Sep;13(12):1532-6. doi: 10.1096/fasebj.13.12.1532. FASEB J. 1999. PMID: 10463944
The variability of the mitochondrial genome in human aging: a key for life and death?
Rose G, Passarino G, Franceschi C, De Benedictis G. Rose G, et al. Int J Biochem Cell Biol. 2002 Nov;34(11):1449-60. doi: 10.1016/s1357-2725(02)00042-0. Int J Biochem Cell Biol. 2002. PMID: 12200038 Review.
Association of the mitochondrial DNA haplogroup J with longevity is population specific.
Dato S, Passarino G, Rose G, Altomare K, Bellizzi D, Mari V, Feraco E, Franceschi C, De Benedictis G. Dato S, et al. Eur J Hum Genet. 2004 Dec;12(12):1080-2. doi: 10.1038/sj.ejhg.5201278. Eur J Hum Genet. 2004. PMID: 15470367
Mitochondrial DNA involvement in human longevity.
Santoro A, Salvioli S, Raule N, Capri M, Sevini F, Valensin S, Monti D, Bellizzi D, Passarino G, Rose G, De Benedictis G, Franceschi C. Santoro A, et al. Biochim Biophys Acta. 2006 Sep-Oct;1757(9-10):1388-99. doi: 10.1016/j.bbabio.2006.05.040. Epub 2006 Jun 7. Biochim Biophys Acta. 2006. PMID: 16857160 Review.
Gene expression of cytokines and cytokine receptors is modulated by the common variability of the mitochondrial DNA in cybrid cell lines.
Bellizzi D, Cavalcante P, Taverna D, Rose G, Passarino G, Salvioli S, Franceschi C, De Benedictis G. Bellizzi D, et al. Genes Cells. 2006 Aug;11(8):883-91. doi: 10.1111/j.1365-2443.2006.00986.x. Genes Cells. 2006. PMID: 16866872
Human longevity within an evolutionary perspective: the peculiar paradigm of a post-reproductive genetics.
Capri M, Salvioli S, Monti D, Caruso C, Candore G, Vasto S, Olivieri F, Marchegiani F, Sansoni P, Baggio G, Mari D, Passarino G, De Benedictis G, Franceschi C. Capri M, et al. Exp Gerontol. 2008 Feb;43(2):53-60. doi: 10.1016/j.exger.2007.06.004. Epub 2007 Jul 1. Exp Gerontol. 2008. PMID: 17692487 Review.
The mitochondrial DNA control region shows genetically correlated levels of heteroplasmy in leukocytes of centenarians and their offspring.
Rose G, Passarino G, Scornaienchi V, Romeo G, Dato S, Bellizzi D, Mari V, Feraco E, Maletta R, Bruni A, Franceschi C, De Benedictis G. Rose G, et al. BMC Genomics. 2007 Aug 29;8:293. doi: 10.1186/1471-2164-8-293. BMC Genomics. 2007. PMID: 17727699 Free PMC article.
The impact of mitochondrial DNA on human lifespan: a view from studies on centenarians.
Salvioli S, Capri M, Santoro A, Raule N, Sevini F, Lukas S, Lanzarini C, Monti D, Passarino G, Rose G, De Benedictis G, Franceschi C. Salvioli S, et al. Biotechnol J. 2008 Jun;3(6):740-9. doi: 10.1002/biot.200800046. Biotechnol J. 2008. PMID: 18548739 Review.
The frequency of Klotho KL-VS polymorphism in a large Italian population, from young subjects to centenarians, suggests the presence of specific time windows for its effect.
Invidia L, Salvioli S, Altilia S, Pierini M, Panourgia MP, Monti D, De Rango F, Passarino G, Franceschi C. Invidia L, et al. Biogerontology. 2010 Feb;11(1):67-73. doi: 10.1007/s10522-009-9229-z. Epub 2009 May 7. Biogerontology. 2010. PMID: 19421891
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