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The Polyanionic Drug Suramin Neutralizes Histones and Prevents Endotheliopathy.
Villalba N, Sackheim AM, Lawson MA, Haines L, Chen YL, Sonkusare SK, Ma YT, Li J, Majumdar D, Bouchard BA, Boyson JE, Poynter ME, Nelson MT, Freeman K. Villalba N, et al. Among authors: sackheim am. J Immunol. 2023 Aug 15;211(4):648-657. doi: 10.4049/jimmunol.2200703. J Immunol. 2023. PMID: 37405700
Extracellular histones induce calcium signals in the endothelium of resistance-sized mesenteric arteries and cause loss of endothelium-dependent dilation.
Collier DM, Villalba N, Sackheim A, Bonev AD, Miller ZD, Moore JS, Shui B, Lee JC, Lee FK, Reining S, Kotlikoff MI, Nelson MT, Freeman K. Collier DM, et al. Am J Physiol Heart Circ Physiol. 2019 Jun 1;316(6):H1309-H1322. doi: 10.1152/ajpheart.00655.2018. Epub 2019 Mar 8. Am J Physiol Heart Circ Physiol. 2019. PMID: 30848676 Free PMC article.
Impaired capillary-to-arteriolar electrical signaling after traumatic brain injury.
Mughal A, Sackheim AM, Sancho M, Longden TA, Russell S, Lockette W, Nelson MT, Freeman K. Mughal A, et al. Among authors: sackheim am. J Cereb Blood Flow Metab. 2021 Jun;41(6):1313-1327. doi: 10.1177/0271678X20962594. Epub 2020 Oct 13. J Cereb Blood Flow Metab. 2021. PMID: 33050826 Free PMC article.
Traumatic brain injury impairs sensorimotor function in mice.
Sackheim AM, Stockwell D, Villalba N, Haines L, Scott CL, Russell S, Hammack SE, Freeman K. Sackheim AM, et al. J Surg Res. 2017 Jun 1;213:100-109. doi: 10.1016/j.jss.2017.02.016. Epub 2017 Feb 23. J Surg Res. 2017. PMID: 28601302 Free PMC article.
12 results