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The C-terminus of non-structural protein 1 (NS1) in H5N8 clade 2.3.4.4 avian influenza virus affects virus fitness in human cells and virulence in mice.
Blaurock C, Blohm U, Luttermann C, Holzerland J, Scheibner D, Schäfer A, Groseth A, Mettenleiter TC, Abdelwhab EM. Blaurock C, et al. Among authors: schafer a. Emerg Microbes Infect. 2021 Dec;10(1):1760-1776. doi: 10.1080/22221751.2021.1971568. Emerg Microbes Infect. 2021. PMID: 34420477 Free PMC article.
Recognition of microbial viability via TLR8 drives TFH cell differentiation and vaccine responses.
Ugolini M, Gerhard J, Burkert S, Jensen KJ, Georg P, Ebner F, Volkers SM, Thada S, Dietert K, Bauer L, Schäfer A, Helbig ET, Opitz B, Kurth F, Sur S, Dittrich N, Gaddam S, Conrad ML, Benn CS, Blohm U, Gruber AD, Hutloff A, Hartmann S, Boekschoten MV, Müller M, Jungersen G, Schumann RR, Suttorp N, Sander LE. Ugolini M, et al. Among authors: schafer a. Nat Immunol. 2018 Apr;19(4):386-396. doi: 10.1038/s41590-018-0068-4. Epub 2018 Mar 19. Nat Immunol. 2018. PMID: 29556002
Genetic incompatibilities and reduced transmission in chickens may limit the evolution of reassortants between H9N2 and panzootic H5N8 clade 2.3.4.4 avian influenza virus showing high virulence for mammals.
Mostafa A, Blaurock C, Scheibner D, Müller C, Blohm U, Schäfer A, Gischke M, Salaheldin AH, Nooh HZ, Ali MA, Breithaupt A, Mettenleiter TC, Pleschka S, Abdelwhab EM. Mostafa A, et al. Among authors: schafer a. Virus Evol. 2020 Oct 15;6(2):veaa077. doi: 10.1093/ve/veaa077. eCollection 2020 Jul. Virus Evol. 2020. PMID: 33343923 Free PMC article.
1,671 results