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SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation.
Yan B, Freiwald T, Chauss D, Wang L, West E, Mirabelli C, Zhang CJ, Nichols EM, Malik N, Gregory R, Bantscheff M, Ghidelli-Disse S, Kolev M, Frum T, Spence JR, Sexton JZ, Alysandratos KD, Kotton DN, Pittaluga S, Bibby J, Niyonzima N, Olson MR, Kordasti S, Portilla D, Wobus CE, Laurence A, Lionakis MS, Kemper C, Afzali B, Kazemian M. Yan B, et al. Among authors: sexton jz. Sci Immunol. 2021 Apr 7;6(58):eabg0833. doi: 10.1126/sciimmunol.abg0833. Sci Immunol. 2021. PMID: 33827897 Free PMC article.
Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19.
Mirabelli C, Wotring JW, Zhang CJ, McCarty SM, Fursmidt R, Frum T, Kadambi NS, Amin AT, O'Meara TR, Pretto CD, Spence JR, Huang J, Alysandratos KD, Kotton DN, Handelman SK, Wobus CE, Weatherwax KJ, Mashour GA, O'Meara MJ, Sexton JZ. Mirabelli C, et al. Among authors: sexton jz. bioRxiv [Preprint]. 2020 Dec 7:2020.05.27.117184. doi: 10.1101/2020.05.27.117184. bioRxiv. 2020. PMID: 32577649 Free PMC article. Updated. Preprint.
SARS-CoV-2 receptor networks in diabetic and COVID-19-associated kidney disease.
Menon R, Otto EA, Sealfon R, Nair V, Wong AK, Theesfeld CL, Chen X, Wang Y, Boppana AS, Luo J, Yang Y, Kasson PM, Schaub JA, Berthier CC, Eddy S, Lienczewski CC, Godfrey B, Dagenais SL, Sohaney R, Hartman J, Fermin D, Subramanian L, Looker HC, Harder JL, Mariani LH, Hodgin JB, Sexton JZ, Wobus CE, Naik AS, Nelson RG, Troyanskaya OG, Kretzler M. Menon R, et al. Among authors: sexton jz. Kidney Int. 2020 Dec;98(6):1502-1518. doi: 10.1016/j.kint.2020.09.015. Epub 2020 Oct 8. Kidney Int. 2020. PMID: 33038424 Free PMC article.
Identification of ACE2 modifiers by CRISPR screening.
Sherman EJ, Mirabelli C, Tang VT, Khan TG, Kennedy AA, Graham SE, Willer CJ, Tai AW, Sexton JZ, Wobus CE, Emmer BT. Sherman EJ, et al. Among authors: sexton jz. bioRxiv [Preprint]. 2021 Jun 10:2021.06.10.447768. doi: 10.1101/2021.06.10.447768. bioRxiv. 2021. PMID: 34127970 Free PMC article. Updated. Preprint.
Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19.
Mirabelli C, Wotring JW, Zhang CJ, McCarty SM, Fursmidt R, Pretto CD, Qiao Y, Zhang Y, Frum T, Kadambi NS, Amin AT, O'Meara TR, Spence JR, Huang J, Alysandratos KD, Kotton DN, Handelman SK, Wobus CE, Weatherwax KJ, Mashour GA, O'Meara MJ, Chinnaiyan AM, Sexton JZ. Mirabelli C, et al. Among authors: sexton jz. Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2105815118. doi: 10.1073/pnas.2105815118. Proc Natl Acad Sci U S A. 2021. PMID: 34413211 Free PMC article.
Identification of cell type specific ACE2 modifiers by CRISPR screening.
Sherman EJ, Mirabelli C, Tang VT, Khan TG, Leix K, Kennedy AA, Graham SE, Willer CJ, Tai AW, Sexton JZ, Wobus CE, Emmer BT. Sherman EJ, et al. Among authors: sexton jz. PLoS Pathog. 2022 Mar 1;18(3):e1010377. doi: 10.1371/journal.ppat.1010377. eCollection 2022 Mar. PLoS Pathog. 2022. PMID: 35231079 Free PMC article.
Mapping the adult human esophagus in vivo and in vitro.
Ferrer-Torres D, Wu JH, Zhang CJ, Hammer MA, Dame MK, Wu A, Holloway EM, Karpoff K, McCarthy CL, Bohm MS, Cuttitta AJ, Tigani DJ, Huang S, Tsai YH, Miller AJ, Walker T, Bayer DE, Hogan SP, Turgeon DK, Lin J, Higgins PDR, Sexton J, Spence JR. Ferrer-Torres D, et al. Development. 2022 Oct 15;149(20):dev200614. doi: 10.1242/dev.200614. Epub 2022 Oct 24. Development. 2022. PMID: 36278875 Free PMC article.
74 results