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Efficacy of OZ439 (artefenomel) against early Plasmodium falciparum blood-stage malaria infection in healthy volunteers.
J Antimicrob Chemother. 2016 Sep;71(9):2620-7. doi: 10.1093/jac/dkw174. Epub 2016 Jun 5.
J Antimicrob Chemother. 2016.
PMID: 27272721
Free PMC article.
Pharmacokinetic/pharmacodynamic modelling of the antimalarial effect of Actelion-451840 in an induced blood stage malaria study in healthy subjects.
Krause A, Dingemanse J, Mathis A, Marquart L, Möhrle JJ, McCarthy JS.
Krause A, et al.
Br J Clin Pharmacol. 2016 Aug;82(2):412-21. doi: 10.1111/bcp.12962. Epub 2016 May 11.
Br J Clin Pharmacol. 2016.
PMID: 27062080
Free PMC article.
Clinical Trial.
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Linking Murine and Human Plasmodium falciparum Challenge Models in a Translational Path for Antimalarial Drug Development.
McCarthy JS, Marquart L, Sekuloski S, Trenholme K, Elliott S, Griffin P, Rockett R, O'Rourke P, Sloots T, Angulo-Barturen I, Ferrer S, Jiménez-Díaz MB, Martínez MS, Hooft van Huijsduijnen R, Duparc S, Leroy D, Wells TN, Baker M, Möhrle JJ.
McCarthy JS, et al.
Antimicrob Agents Chemother. 2016 May 23;60(6):3669-75. doi: 10.1128/AAC.02883-15. Print 2016 Jun.
Antimicrob Agents Chemother. 2016.
PMID: 27044554
Free PMC article.
Clinical Trial.
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