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Plasma and CSF concentrations of N-terminal tau fragments associate with in vivo neurofibrillary tangle burden.
Lantero-Rodriguez J, Tissot C, Snellman A, Servaes S, Benedet AL, Rahmouni N, Montoliu-Gaya L, Therriault J, Brum WS, Stevenson J, Lussier FZ, Bezgin G, Macedo AC, Chamoun M, Mathotaarachi SS, Pascoal TA, Ashton NJ, Zetterberg H, Neto PR, Blennow K. Lantero-Rodriguez J, et al. Alzheimers Dement. 2023 Dec;19(12):5343-5354. doi: 10.1002/alz.13119. Epub 2023 May 15. Alzheimers Dement. 2023. PMID: 37190913
18F-MK-6240 PET for early and late detection of neurofibrillary tangles.
Pascoal TA, Therriault J, Benedet AL, Savard M, Lussier FZ, Chamoun M, Tissot C, Qureshi MNI, Kang MS, Mathotaarachchi S, Stevenson J, Hopewell R, Massarweh G, Soucy JP, Gauthier S, Rosa-Neto P. Pascoal TA, et al. Brain. 2020 Sep 1;143(9):2818-2830. doi: 10.1093/brain/awaa180. Brain. 2020. PMID: 32671408
Plasma pTau-217 and N-terminal tau (NTA) enhance sensitivity to identify tau PET positivity in amyloid-β positive individuals.
Woo MS, Tissot C, Lantero-Rodriguez J, Snellman A, Therriault J, Rahmouni N, Macedo AC, Servaes S, Wang YT, Arias JF, Hosseini SA, Chamoun M, Lussier FZ, Benedet AL, Ashton NJ, Karikari TK, Triana-Baltzer G, Kolb HC, Stevenson J, Mayer C, Kobayashi E, Massarweh G, Friese MA, Pascoal TA, Gauthier S, Zetterberg H, Blennow K, Rosa-Neto P. Woo MS, et al. Alzheimers Dement. 2024 Feb;20(2):1166-1174. doi: 10.1002/alz.13528. Epub 2023 Nov 3. Alzheimers Dement. 2024. PMID: 37920945 Free PMC article.
Soluble amyloid-beta isoforms predict downstream Alzheimer's disease pathology.
Povala G, Bellaver B, De Bastiani MA, Brum WS, Ferreira PCL, Bieger A, Pascoal TA, Benedet AL, Souza DO, Araujo RM, Zatt B, Rosa-Neto P, Zimmer ER; for the Alzheimer’s Disease Neuroimaging Initiative. Povala G, et al. Cell Biosci. 2021 Dec 11;11(1):204. doi: 10.1186/s13578-021-00712-3. Cell Biosci. 2021. PMID: 34895338 Free PMC article.