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Contact-Dependent Granzyme B-Mediated Cytotoxicity of Th17-Polarized Cells Toward Human Oligodendrocytes.
Jamann H, Cui QL, Desu HL, Pernin F, Tastet O, Halaweh A, Farzam-Kia N, Mamane VH, Ouédraogo O, Cleret-Buhot A, Daigneault A, Balthazard R, Klement W, Lemaître F, Arbour N, Antel J, Stratton JA, Larochelle C. Jamann H, et al. Front Immunol. 2022 Apr 11;13:850616. doi: 10.3389/fimmu.2022.850616. eCollection 2022. Front Immunol. 2022. PMID: 35479072 Free PMC article.
Pro-inflammatory T helper 17 directly harms oligodendrocytes in neuroinflammation.
Larochelle C, Wasser B, Jamann H, Löffel JT, Cui QL, Tastet O, Schillner M, Luchtman D, Birkenstock J, Stroh A, Antel J, Bittner S, Zipp F. Larochelle C, et al. Proc Natl Acad Sci U S A. 2021 Aug 24;118(34):e2025813118. doi: 10.1073/pnas.2025813118. Proc Natl Acad Sci U S A. 2021. PMID: 34417310 Free PMC article.