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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
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2009 | 1 |
2010 | 4 |
2011 | 1 |
2024 | 0 |
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Heterobiaryl and heterobiaryl ether derived M5 positive allosteric modulators.
Bioorg Med Chem Lett. 2010 Oct 1;20(19):5617-22. doi: 10.1016/j.bmcl.2010.08.042. Epub 2010 Aug 12.
Bioorg Med Chem Lett. 2010.
PMID: 20801651
Free PMC article.
Discovery and optimization of a novel, selective and brain penetrant M1 positive allosteric modulator (PAM): the development of ML169, an MLPCN probe.
Reid PR, Bridges TM, Sheffler DJ, Cho HP, Lewis LM, Days E, Daniels JS, Jones CK, Niswender CM, Weaver CD, Conn PJ, Lindsley CW, Wood MR.
Reid PR, et al.
Bioorg Med Chem Lett. 2011 May 1;21(9):2697-701. doi: 10.1016/j.bmcl.2010.12.015. Epub 2010 Dec 9.
Bioorg Med Chem Lett. 2011.
PMID: 21194936
Free PMC article.
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Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part II: development of a potent and highly selective M1 PAM.
Bridges TM, Phillip Kennedy J, Noetzel MJ, Breininger ML, Gentry PR, Conn PJ, Lindsley CW.
Bridges TM, et al.
Bioorg Med Chem Lett. 2010 Mar 15;20(6):1972-5. doi: 10.1016/j.bmcl.2010.01.109. Epub 2010 Feb 1.
Bioorg Med Chem Lett. 2010.
PMID: 20156687
Free PMC article.
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Chemical lead optimization of a pan G(q) mAChR M(1), M(3), M(5) positive allosteric modulator (PAM) lead. Part I: Development of the first highly selective M(5) PAM.
Bridges TM, Kennedy JP, Cho HP, Breininger ML, Gentry PR, Hopkins CR, Conn PJ, Lindsley CW.
Bridges TM, et al.
Bioorg Med Chem Lett. 2010 Jan 15;20(2):558-62. doi: 10.1016/j.bmcl.2009.11.089. Epub 2009 Nov 22.
Bioorg Med Chem Lett. 2010.
PMID: 20004578
Free PMC article.
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