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Antiphospholipid antibodies and the antiphospholipid syndrome: pathogenic mechanisms.
Semin Thromb Hemost. 2008 Apr;34(3):236-50. doi: 10.1055/s-0028-1082267.
Semin Thromb Hemost. 2008.
PMID: 18720303
Review.
It is generally accepted that the major autoantigen for aPL Abs is beta (2) glycoprotein I, which mediates the binding of aPL Abs to target cells (i.e., endothelial cells, monocytes, platelets, trophoblasts, etc.) leading to thrombosis and fetal loss. ...
It is generally accepted that the major autoantigen for aPL Abs is beta (2) glycoprotein I, which mediates the binding of aPL Abs to …
Assessment of the item selection and weighting in the Birmingham vasculitis activity score for Wegener's granulomatosis.
Mahr AD, Neogi T, Lavalley MP, Davis JC, Hoffman GS, McCune WJ, Specks U, Spiera RF, St Clair EW, Stone JH, Merkel PA; Wegener's Granulomatosis Etanercept Trial Research Group.
Mahr AD, et al.
Arthritis Rheum. 2008 Jun 15;59(6):884-91. doi: 10.1002/art.23707.
Arthritis Rheum. 2008.
PMID: 18512722
Free PMC article.
We searched for the model that included the items and their generated weights yielding an activity score with the highest R(2) to predict the PGA. RESULTS: We analyzed 2,044 BVAS/WG assessments from 180 patients; 734 assessments were scored during active disease. Th …
We searched for the model that included the items and their generated weights yielding an activity score with the highest R(2) to pre …
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