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Synthesis, binding affinity, radiolabeling, and microPET evaluation of 4-(2-substituted-4-substituted)-8-(dialkylamino)-6-methyl-1-substituted-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-ones as ligands for brain corticotropin-releasing factor type-1 (CRF1) receptors.
Stehouwer JS, Bourke CH, Owens MJ, Voll RJ, Kilts CD, Goodman MM. Stehouwer JS, et al. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5111-4. doi: 10.1016/j.bmcl.2015.10.010. Epub 2015 Oct 8. Bioorg Med Chem Lett. 2015. PMID: 26456805 Free PMC article.
Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor.
Stehouwer JS, Birnbaum MS, Voll RJ, Owens MJ, Plott SJ, Bourke CH, Wassef MA, Kilts CD, Goodman MM. Stehouwer JS, et al. Bioorg Med Chem. 2015 Aug 1;23(15):4286-4302. doi: 10.1016/j.bmc.2015.06.036. Epub 2015 Jun 19. Bioorg Med Chem. 2015. PMID: 26145817 Free PMC article.