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Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria.
Proc Natl Acad Sci U S A. 2006 May 2;103(18):7142-7. doi: 10.1073/pnas.0602046103. Epub 2006 Apr 24.
Proc Natl Acad Sci U S A. 2006.
PMID: 16636275
Free PMC article.
Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice.
Furukawa Y, Fu R, Deng HX, Siddique T, O'Halloran TV.
Furukawa Y, et al.
Proc Natl Acad Sci U S A. 2006 May 2;103(18):7148-53. doi: 10.1073/pnas.0602048103. Epub 2006 Apr 24.
Proc Natl Acad Sci U S A. 2006.
PMID: 16636274
Free PMC article.
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