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Design of Nanoparticles in Cancer Therapy Based on Tumor Microenvironment Properties.
Mahdavi Firouzabadi B, Gigliobianco MR, Joseph JM, Censi R, Di Martino P. Mahdavi Firouzabadi B, et al. Pharmaceutics. 2022 Dec 3;14(12):2708. doi: 10.3390/pharmaceutics14122708. Pharmaceutics. 2022. PMID: 36559202 Free PMC article. Review.
Cancer is one of the leading causes of death worldwide, and battling cancer has always been a challenging subject in medical sciences. ...During the past few decades, nanoparticles (NPs) have attracted much attention for the delivery of therapeutic and diagnostic ag …
Cancer is one of the leading causes of death worldwide, and battling cancer has always been a challenging subject in medical s …
Granulocytes and Cells of Granulocyte Origin-The Relevant Players in Colorectal Cancer.
Siemińska I, Poljańska E, Baran J. Siemińska I, et al. Int J Mol Sci. 2021 Apr 6;22(7):3801. doi: 10.3390/ijms22073801. Int J Mol Sci. 2021. PMID: 33917620 Free PMC article. Review.
Colorectal cancer (CRC) is one of the most common malignancy and cause of cancer death worldwide, and it still remains a therapeutic challenge for western medicine. ...
Colorectal cancer (CRC) is one of the most common malignancy and cause of cancer death worldwide, and it still remains a thera …
Functionalized Nanoparticles Targeting Tumor-Associated Macrophages as Cancer Therapy.
He Y, de Araújo Júnior RF, Cruz LJ, Eich C. He Y, et al. Pharmaceutics. 2021 Oct 13;13(10):1670. doi: 10.3390/pharmaceutics13101670. Pharmaceutics. 2021. PMID: 34683963 Free PMC article. Review.
Nanomedicine formulations that prevent TAM signaling and recruitment to the TME or deplete M2 TAMs to reduce tumor growth and metastasis represent encouraging novel strategies in cancer therapy. They allow the specific delivery of antitumor drugs to the tumor area, thereby …
Nanomedicine formulations that prevent TAM signaling and recruitment to the TME or deplete M2 TAMs to reduce tumor growth and metastasis rep …
Multifunctional Role of Lipids in Modulating the Tumorigenic Properties of 4T1 Breast Cancer Cells.
He Y, Rezaei S, Júnior RFA, Cruz LJ, Eich C. He Y, et al. Int J Mol Sci. 2022 Apr 11;23(8):4240. doi: 10.3390/ijms23084240. Int J Mol Sci. 2022. PMID: 35457057 Free PMC article.
Our results highlight a powerful role for exogenously applied PA and Cer in reducing breast cancer tumorigenicity by simultaneously targeting cancer cells and M2 macrophages. Our findings support the notion that lipids represent alternative biocompatible therapeutic …
Our results highlight a powerful role for exogenously applied PA and Cer in reducing breast cancer tumorigenicity by simultaneously t …
Applications of Noble Metal-Based Nanoparticles in Medicine.
Klębowski B, Depciuch J, Parlińska-Wojtan M, Baran J. Klębowski B, et al. Int J Mol Sci. 2018 Dec 13;19(12):4031. doi: 10.3390/ijms19124031. Int J Mol Sci. 2018. PMID: 30551592 Free PMC article. Review.
Similarities in the General Chemical Composition of Colon Cancer Cells and Their Microvesicles Investigated by Spectroscopic Methods-Potential Clinical Relevance.
Depciuch J, Klębowski B, Stec M, Szatanek R, Węglarczyk K, Baj-Krzyworzeka M, Parlińska-Wojtan M, Baran J. Depciuch J, et al. Int J Mol Sci. 2020 Mar 6;21(5):1826. doi: 10.3390/ijms21051826. Int J Mol Sci. 2020. PMID: 32155840 Free PMC article.
Colon cancer constitutes 33% of all cancer cases in humans and the majority of patients with metastatic colon cancer still have poor prognosis. An important role in cancer development is the communication between cancer and normal cells. ...
Colon cancer constitutes 33% of all cancer cases in humans and the majority of patients with metastatic colon cancer st …
Improving the Effect of Cancer Cells Irradiation with X-rays and High-Energy Protons Using Bimetallic Palladium-Platinum Nanoparticles with Various Nanostructures.
Klebowski B, Stec M, Depciuch J, Panek A, Krzempek D, Komenda W, Gałuszka-Bulaga A, Pajor-Swierzy A, Baran J, Parlinska-Wojtan M. Klebowski B, et al. Cancers (Basel). 2022 Nov 29;14(23):5899. doi: 10.3390/cancers14235899. Cancers (Basel). 2022. PMID: 36497386 Free PMC article.
Scanning transmission electron microscopy (STEM), selected area electron diffraction (SAED), energy-dispersive X-ray spectroscopy (EDS), zeta potential measurements, and nanoparticle tracking analysis (NTA) were used to provide the physicochemical characteristics of PdPt NPs. The …
Scanning transmission electron microscopy (STEM), selected area electron diffraction (SAED), energy-dispersive X-ray spectroscopy (EDS), zet …
Dually Cross-Linked Core-Shell Structure Nanohydrogel with Redox-Responsive Degradability for Intracellular Delivery.
Deng S, Gigliobianco MR, Mijit E, Minicucci M, Cortese M, Campisi B, Voinovich D, Battistelli M, Salucci S, Gobbi P, Lupidi G, Zambito G, Mezzanotte L, Censi R, Di Martino P. Deng S, et al. Pharmaceutics. 2021 Nov 30;13(12):2048. doi: 10.3390/pharmaceutics13122048. Pharmaceutics. 2021. PMID: 34959330 Free PMC article.
Therefore, the developed core-shell structure nanohydrogel can be considered a promising tool for the potential intracellular delivery of different pharmaceutical applications, including for cancer therapy....
Therefore, the developed core-shell structure nanohydrogel can be considered a promising tool for the potential intracellular delivery of di …
Bacterial Cellulose as Drug Delivery System for Optimizing Release of Immune Checkpoint Blocking Antibodies.
Chung CK, Beekmann U, Kralisch D, Bierau K, Chan A, Ossendorp F, Cruz LJ. Chung CK, et al. Pharmaceutics. 2022 Jun 25;14(7):1351. doi: 10.3390/pharmaceutics14071351. Pharmaceutics. 2022. PMID: 35890247 Free PMC article.
Immune checkpoint blocking therapy is a promising cancer treatment modality, though it has limitations such as systemic toxicity, which can often be traced to uncontrolled antibody spread. ...
Immune checkpoint blocking therapy is a promising cancer treatment modality, though it has limitations such as systemic toxicity, whi …
15 results