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27-Hydroxycholesterol contributes to cognitive deficits in APP/PS1 transgenic mice through microbiota dysbiosis and intestinal barrier dysfunction.
J Neuroinflammation. 2020 Jun 27;17(1):199. doi: 10.1186/s12974-020-01873-7.
J Neuroinflammation. 2020.
PMID: 32593306
Free PMC article.
Regulation of Th17/Treg Balance by 27-Hydroxycholesterol and 24S-Hydroxycholesterol Correlates with Learning and Memory Ability in Mice.
Wang T, Cui S, Hao L, Liu W, Wang L, Ju M, Feng W, Xiao R.
Wang T, et al.
Int J Mol Sci. 2022 Apr 15;23(8):4370. doi: 10.3390/ijms23084370.
Int J Mol Sci. 2022.
PMID: 35457188
Free PMC article.
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27-hydroxycholesterol causes cognitive deficits by disturbing Th17/Treg balance and the related immune responses in mild cognitive impairment patients and C57BL/6J mice.
Wang T, Feng W, Ju M, Yu H, Guo Z, Sun X, Yang K, Liu M, Xiao R.
Wang T, et al.
J Neuroinflammation. 2023 Dec 19;20(1):305. doi: 10.1186/s12974-023-02986-5.
J Neuroinflammation. 2023.
PMID: 38115100
Free PMC article.
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Patterns of cognitive function in middle-aged and elderly Chinese adults-findings from the EMCOA study.
An Y, Feng L, Zhang X, Wang Y, Wang Y, Tao L, Lu Y, Qin Z, Xiao R.
An Y, et al.
Alzheimers Res Ther. 2018 Sep 15;10(1):93. doi: 10.1186/s13195-018-0421-8.
Alzheimers Res Ther. 2018.
PMID: 30219087
Free PMC article.
Clinical Trial.
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Roseburia intestinalis Supplementation Could Reverse the Learning and Memory Impairment and m6A Methylation Modification Decrease Caused by 27-Hydroxycholesterol in Mice.
Sun X, Zhou C, Ju M, Feng W, Guo Z, Qi C, Yang K, Xiao R.
Sun X, et al.
Nutrients. 2024 Apr 26;16(9):1288. doi: 10.3390/nu16091288.
Nutrients. 2024.
PMID: 38732535
Free PMC article.
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