AI043957/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2002	2
2007	1
2008	2
2009	4
2010	4
2011	2
2012	4
2013	2
2014	3
2015	2
2016	2
2017	2
2019	3
2020	3
2021	2
2022	5
2023	2
2024	1

1

Editorial: Targeting Bruton Tyrosine Kinase.

Brunner C, Betzler AC, Brown JR, Andreotti AH, Grassilli E. Brunner C, et al. Front Cell Dev Biol. 2022 Apr 26;10:909655. doi: 10.3389/fcell.2022.909655. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35557950 Free PMC article. No abstract available.

2

Dynamic regulatory features of the protein tyrosine kinases.

Amatya N, Lin DY, Andreotti AH. Amatya N, et al. Biochem Soc Trans. 2019 Aug 30;47(4):1101-1116. doi: 10.1042/BST20180590. Epub 2019 Aug 8. Biochem Soc Trans. 2019. PMID: 31395755 Free PMC article. Review.

3

Conformational switches that control the TEC kinase - PLCγ signaling axis.

Lowe J, Joseph RE, Andreotti AH. Lowe J, et al. J Struct Biol X. 2022 Jan 22;6:100061. doi: 10.1016/j.yjsbx.2022.100061. eCollection 2022. J Struct Biol X. 2022. PMID: 35128378 Free PMC article. Review.

4

Complementarity of Hydrogen/Deuterium Exchange Mass Spectrometry and Cryo-Electron Microscopy.

Engen JR, Komives EA. Engen JR, et al. Trends Biochem Sci. 2020 Oct;45(10):906-918. doi: 10.1016/j.tibs.2020.05.005. Epub 2020 May 30. Trends Biochem Sci. 2020. PMID: 32487353 Free PMC article. Review.

5

Reining in BTK: Interdomain Interactions and Their Importance in the Regulatory Control of BTK.

Kueffer LE, Joseph RE, Andreotti AH. Kueffer LE, et al. Front Cell Dev Biol. 2021 Jun 23;9:655489. doi: 10.3389/fcell.2021.655489. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34249912 Free PMC article. Review.

6

T-cell signaling regulated by the Tec family kinase, Itk.

Andreotti AH, Schwartzberg PL, Joseph RE, Berg LJ. Andreotti AH, et al. Cold Spring Harb Perspect Biol. 2010 Jul;2(7):a002287. doi: 10.1101/cshperspect.a002287. Epub 2010 Jun 2. Cold Spring Harb Perspect Biol. 2010. PMID: 20519342 Free PMC article. Review.

7

Dynamics of the Tec-family tyrosine kinase SH3 domains.

Roberts JM, Tarafdar S, Joseph RE, Andreotti AH, Smithgall TE, Engen JR, Wales TE. Roberts JM, et al. Protein Sci. 2016 Apr;25(4):852-64. doi: 10.1002/pro.2887. Epub 2016 Mar 18. Protein Sci. 2016. PMID: 26808198 Free PMC article.

8

Structure of BTK kinase domain with the second-generation inhibitors acalabrutinib and tirabrutinib.

Lin DY, Andreotti AH. Lin DY, et al. PLoS One. 2023 Aug 31;18(8):e0290872. doi: 10.1371/journal.pone.0290872. eCollection 2023. PLoS One. 2023. PMID: 37651403 Free PMC article.

9

The HIV-1 protein Nef activates the Tec family kinase Btk by stabilizing an intermolecular SH3-SH2 domain interaction.

Aryal M, Lin D, Regan K, Du S, Shi H, Alvarado JJ, Ilina TV, Andreotti AH, Smithgall TE. Aryal M, et al. Sci Signal. 2022 Sep 20;15(752):eabn8359. doi: 10.1126/scisignal.abn8359. Epub 2022 Sep 20. Sci Signal. 2022. PMID: 36126115 Free PMC article.

10

The Conformational State of the BTK Substrate PLCγ Contributes to Ibrutinib Resistance.

Joseph RE, Lowe J, Fulton DB, Engen JR, Wales TE, Andreotti AH. Joseph RE, et al. J Mol Biol. 2022 Mar 15;434(5):167422. doi: 10.1016/j.jmb.2021.167422. Epub 2021 Dec 23. J Mol Biol. 2022. PMID: 34954235 Free PMC article.

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