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Kinesin light chain-1 serine-460 phosphorylation is altered in Alzheimer's disease and regulates axonal transport and processing of the amyloid precursor protein.
Acta Neuropathol Commun. 2019 Dec 5;7(1):200. doi: 10.1186/s40478-019-0857-5.
Acta Neuropathol Commun. 2019.
PMID: 31806024
Free PMC article.
LMTK2 binds to kinesin light chains to mediate anterograde axonal transport of cdk5/p35 and LMTK2 levels are reduced in Alzheimer's disease brains.
Mórotz GM, Glennon EB, Gomez-Suaga P, Lau DHW, Robinson ED, Sedlák É, Vagnoni A, Noble W, Miller CCJ.
Mórotz GM, et al.
Acta Neuropathol Commun. 2019 May 8;7(1):73. doi: 10.1186/s40478-019-0715-5.
Acta Neuropathol Commun. 2019.
PMID: 31068217
Free PMC article.
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Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons.
Rodríguez-Martín T, Pooler AM, Lau DHW, Mórotz GM, De Vos KJ, Gilley J, Coleman MP, Hanger DP.
Rodríguez-Martín T, et al.
Neurobiol Dis. 2016 Jan;85:1-10. doi: 10.1016/j.nbd.2015.10.007. Epub 2015 Oct 11.
Neurobiol Dis. 2016.
PMID: 26459111
Free PMC article.
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