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Year Number of Results
2018 4
2019 5
2020 2
2021 4
2022 1
2023 1
2024 0

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16 results

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Page 1
STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma.
Adane B, Alexe G, Seong BKA, Lu D, Hwang EE, Hnisz D, Lareau CA, Ross L, Lin S, Dela Cruz FS, Richardson M, Weintraub AS, Wang S, Iniguez AB, Dharia NV, Conway AS, Robichaud AL, Tanenbaum B, Krill-Burger JM, Vazquez F, Schenone M, Berman JN, Kung AL, Carr SA, Aryee MJ, Young RA, Crompton BD, Stegmaier K. Adane B, et al. Cancer Cell. 2021 Jun 14;39(6):827-844.e10. doi: 10.1016/j.ccell.2021.05.007. Cancer Cell. 2021. PMID: 34129824 Free PMC article.
TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma.
Seong BKA, Dharia NV, Lin S, Donovan KA, Chong S, Robichaud A, Conway A, Hamze A, Ross L, Alexe G, Adane B, Nabet B, Ferguson FM, Stolte B, Wang EJ, Sun J, Darzacq X, Piccioni F, Gray NS, Fischer ES, Stegmaier K. Seong BKA, et al. Cancer Cell. 2021 Sep 13;39(9):1262-1278.e7. doi: 10.1016/j.ccell.2021.07.003. Epub 2021 Jul 29. Cancer Cell. 2021. PMID: 34329586 Free PMC article.
EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma.
Gorthi A, Romero JC, Loranc E, Cao L, Lawrence LA, Goodale E, Iniguez AB, Bernard X, Masamsetti VP, Roston S, Lawlor ER, Toretsky JA, Stegmaier K, Lessnick SL, Chen Y, Bishop AJR. Gorthi A, et al. Nature. 2018 Mar 15;555(7696):387-391. doi: 10.1038/nature25748. Epub 2018 Mar 7. Nature. 2018. PMID: 29513652 Free PMC article.
A first-generation pediatric cancer dependency map.
Dharia NV, Kugener G, Guenther LM, Malone CF, Durbin AD, Hong AL, Howard TP, Bandopadhayay P, Wechsler CS, Fung I, Warren AC, Dempster JM, Krill-Burger JM, Paolella BR, Moh P, Jha N, Tang A, Montgomery P, Boehm JS, Hahn WC, Roberts CWM, McFarland JM, Tsherniak A, Golub TR, Vazquez F, Stegmaier K. Dharia NV, et al. Nat Genet. 2021 Apr;53(4):529-538. doi: 10.1038/s41588-021-00819-w. Epub 2021 Mar 22. Nat Genet. 2021. PMID: 33753930 Free PMC article.
Highly connected 3D chromatin networks established by an oncogenic fusion protein shape tumor cell identity.
Sanalkumar R, Dong R, Lee L, Xing YH, Iyer S, Letovanec I, La Rosa S, Finzi G, Musolino E, Papait R, Chebib I, Nielsen GP, Renella R, Cote GM, Choy E, Aryee M, Stegmaier K, Stamenkovic I, Rivera MN, Riggi N. Sanalkumar R, et al. Sci Adv. 2023 Mar 31;9(13):eabo3789. doi: 10.1126/sciadv.abo3789. Epub 2023 Mar 31. Sci Adv. 2023. PMID: 37000878 Free PMC article.
A Combination CDK4/6 and IGF1R Inhibitor Strategy for Ewing Sarcoma.
Guenther LM, Dharia NV, Ross L, Conway A, Robichaud AL, Catlett JL 2nd, Wechsler CS, Frank ES, Goodale A, Church AJ, Tseng YY, Guha R, McKnight CG, Janeway KA, Boehm JS, Mora J, Davis MI, Alexe G, Piccioni F, Stegmaier K. Guenther LM, et al. Clin Cancer Res. 2019 Feb 15;25(4):1343-1357. doi: 10.1158/1078-0432.CCR-18-0372. Epub 2018 Nov 5. Clin Cancer Res. 2019. PMID: 30397176 Free PMC article.
Adverse prognostic impact of the loss of STAG2 protein expression in patients with newly diagnosed localised Ewing sarcoma: A report from the Children's Oncology Group.
Shulman DS, Chen S, Hall D, Nag A, Thorner AR, Lessnick SL, Stegmaier K, Janeway KA, DuBois SG, Krailo MD, Barkauskas DA, Church AJ, Crompton BD. Shulman DS, et al. Br J Cancer. 2022 Dec;127(12):2220-2226. doi: 10.1038/s41416-022-01977-2. Epub 2022 Oct 11. Br J Cancer. 2022. PMID: 36221002 Free PMC article.
16 results