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Inflammasome inhibition blocks cardiac glycoside cell toxicity.
LaRock DL, Sands JS, Ettouati E, Richard M, Bushway PJ, Adler ED, Nizet V, LaRock CN. LaRock DL, et al. J Biol Chem. 2019 Aug 23;294(34):12846-12854. doi: 10.1074/jbc.RA119.008330. Epub 2019 Jul 12. J Biol Chem. 2019. PMID: 31300552 Free PMC article.
The Pseudomonas aeruginosa protease LasB directly activates IL-1β.
Sun J, LaRock DL, Skowronski EA, Kimmey JM, Olson J, Jiang Z, O'Donoghue AJ, Nizet V, LaRock CN. Sun J, et al. EBioMedicine. 2020 Oct;60:102984. doi: 10.1016/j.ebiom.2020.102984. Epub 2020 Sep 23. EBioMedicine. 2020. PMID: 32979835 Free PMC article.