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Dynamic loading stimulates chondrocyte biosynthesis when encapsulated in charged hydrogels prepared from poly(ethylene glycol) and chondroitin sulfate.
Matrix Biol. 2010 Jan;29(1):51-62. doi: 10.1016/j.matbio.2009.08.004. Epub 2009 Aug 29.
Matrix Biol. 2010.
PMID: 19720146
Free PMC article.
Gel structure has an impact on pericellular and extracellular matrix deposition, which subsequently alters metabolic activities in chondrocyte-laden PEG hydrogels.
Nicodemus GD, Skaalure SC, Bryant SJ.
Nicodemus GD, et al.
Acta Biomater. 2011 Feb;7(2):492-504. doi: 10.1016/j.actbio.2010.08.021. Epub 2010 Sep 8.
Acta Biomater. 2011.
PMID: 20804868
Free PMC article.
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Incorporation of biomimetic matrix molecules in PEG hydrogels enhances matrix deposition and reduces load-induced loss of chondrocyte-secreted matrix.
Roberts JJ, Nicodemus GD, Giunta S, Bryant SJ.
Roberts JJ, et al.
J Biomed Mater Res A. 2011 Jun 1;97(3):281-91. doi: 10.1002/jbm.a.33057. Epub 2011 Mar 25.
J Biomed Mater Res A. 2011.
PMID: 21442729
Free PMC article.
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