R01 CA100045-04/CA/NCI NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2007	2
2008	4
2009	3
2011	1
2012	1
2024	0

1

Alpha-tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II.

Dong LF, Low P, Dyason JC, Wang XF, Prochazka L, Witting PK, Freeman R, Swettenham E, Valis K, Liu J, Zobalova R, Turanek J, Spitz DR, Domann FE, Scheffler IE, Ralph SJ, Neuzil J. Dong LF, et al. Oncogene. 2008 Jul 17;27(31):4324-35. doi: 10.1038/onc.2008.69. Epub 2008 Mar 31. Oncogene. 2008. PMID: 18372923 Free PMC article.

2

2-Deoxyglucose combined with wild-type p53 overexpression enhances cytotoxicity in human prostate cancer cells via oxidative stress.

Ahmad IM, Abdalla MY, Aykin-Burns N, Simons AL, Oberley LW, Domann FE, Spitz DR. Ahmad IM, et al. Free Radic Biol Med. 2008 Mar 1;44(5):826-34. doi: 10.1016/j.freeradbiomed.2007.11.007. Epub 2007 Nov 28. Free Radic Biol Med. 2008. PMID: 18155176 Free PMC article.

3

Hydrogen peroxide mediates the radiation-induced mutator phenotype in mammalian cells.

Dayal D, Martin SM, Limoli CL, Spitz DR. Dayal D, et al. Biochem J. 2008 Jul 1;413(1):185-91. doi: 10.1042/BJ20071643. Biochem J. 2008. PMID: 18352860 Free PMC article.

4

Mitochondrial complex II dysfunction can contribute significantly to genomic instability after exposure to ionizing radiation.

Dayal D, Martin SM, Owens KM, Aykin-Burns N, Zhu Y, Boominathan A, Pain D, Limoli CL, Goswami PC, Domann FE, Spitz DR. Dayal D, et al. Radiat Res. 2009 Dec;172(6):737-45. doi: 10.1667/RR1617.1. Radiat Res. 2009. PMID: 19929420 Free PMC article.

5

Manganese superoxide dismutase gene dosage affects chromosomal instability and tumor onset in a mouse model of T cell lymphoma.

van de Wetering CI, Coleman MC, Spitz DR, Smith BJ, Knudson CM. van de Wetering CI, et al. Free Radic Biol Med. 2008 Apr 15;44(8):1677-86. doi: 10.1016/j.freeradbiomed.2008.01.022. Epub 2008 Feb 7. Free Radic Biol Med. 2008. PMID: 18291119 Free PMC article.

6

Simultaneous inhibition of glutathione- and thioredoxin-dependent metabolism is necessary to potentiate 17AAG-induced cancer cell killing via oxidative stress.

Scarbrough PM, Mapuskar KA, Mattson DM, Gius D, Watson WH, Spitz DR. Scarbrough PM, et al. Free Radic Biol Med. 2012 Jan 15;52(2):436-43. doi: 10.1016/j.freeradbiomed.2011.10.493. Epub 2011 Nov 4. Free Radic Biol Med. 2012. PMID: 22100505 Free PMC article.

7

Mitochondrial electron transport chain blockers enhance 2-deoxy-D-glucose induced oxidative stress and cell killing in human colon carcinoma cells.

Fath MA, Diers AR, Aykin-Burns N, Simons AL, Hua L, Spitz DR. Fath MA, et al. Cancer Biol Ther. 2009 Jul;8(13):1228-36. doi: 10.4161/cbt.8.13.8631. Epub 2009 Jul 6. Cancer Biol Ther. 2009. PMID: 19411865 Free PMC article.

8

Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation.

Aykin-Burns N, Ahmad IM, Zhu Y, Oberley LW, Spitz DR. Aykin-Burns N, et al. Biochem J. 2009 Feb 15;418(1):29-37. doi: 10.1042/BJ20081258. Biochem J. 2009. PMID: 18937644 Free PMC article.

9

Enhanced response of human head and neck cancer xenograft tumors to cisplatin combined with 2-deoxy-D-glucose correlates with increased 18F-FDG uptake as determined by PET imaging.

Simons AL, Fath MA, Mattson DM, Smith BJ, Walsh SA, Graham MM, Hichwa RD, Buatti JM, Dornfeld K, Spitz DR. Simons AL, et al. Int J Radiat Oncol Biol Phys. 2007 Nov 15;69(4):1222-30. doi: 10.1016/j.ijrobp.2007.07.2343. Int J Radiat Oncol Biol Phys. 2007. PMID: 17967311 Free PMC article.

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