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Page 1
MATE1 Deficiency Exacerbates Dofetilide-Induced Proarrhythmia.
Uddin ME, Eisenmann ED, Li Y, Huang KM, Garrison DA, Talebi Z, Gibson AA, Jin Y, Nepal M, Bonilla IM, Fu Q, Sun X, Millar A, Tarasov M, Jay CE, Cui X, Einolf HJ, Pelis RM, Smith SA, Radwański PB, Sweet DH, König J, Fromm MF, Carnes CA, Hu S, Sparreboom A. Uddin ME, et al. Int J Mol Sci. 2022 Aug 3;23(15):8607. doi: 10.3390/ijms23158607. Int J Mol Sci. 2022. PMID: 35955741 Free PMC article.
Targeting OCT3 attenuates doxorubicin-induced cardiac injury.
Huang KM, Zavorka Thomas M, Magdy T, Eisenmann ED, Uddin ME, DiGiacomo DF, Pan A, Keiser M, Otter M, Xia SH, Li Y, Jin Y, Fu Q, Gibson AA, Bonilla IM, Carnes CA, Corps KN, Coppola V, Smith SA, Addison D, Nies AT, Bundschuh R, Chen T, Lustberg MB, Wang J, Oswald S, Campbell MJ, Yan PS, Baker SD, Hu S, Burridge PW, Sparreboom A. Huang KM, et al. Proc Natl Acad Sci U S A. 2021 Feb 2;118(5):e2020168118. doi: 10.1073/pnas.2020168118. Proc Natl Acad Sci U S A. 2021. PMID: 33495337 Free PMC article.
OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity.
Leblanc AF, Sprowl JA, Alberti P, Chiorazzi A, Arnold WD, Gibson AA, Hong KW, Pioso MS, Chen M, Huang KM, Chodisetty V, Costa O, Florea T, de Bruijn P, Mathijssen RH, Reinbolt RE, Lustberg MB, Sucheston-Campbell LE, Cavaletti G, Sparreboom A, Hu S. Leblanc AF, et al. J Clin Invest. 2018 Feb 1;128(2):816-825. doi: 10.1172/JCI96160. Epub 2018 Jan 16. J Clin Invest. 2018. PMID: 29337310 Free PMC article.
Regulation of OATP1B1 Function by Tyrosine Kinase-mediated Phosphorylation.
Hayden ER, Chen M, Pasquariello KZ, Gibson AA, Petti JJ, Shen S, Qu J, Ong SS, Chen T, Jin Y, Uddin ME, Huang KM, Paz A, Sparreboom A, Hu S, Sprowl JA. Hayden ER, et al. Clin Cancer Res. 2021 Aug 1;27(15):4301-4310. doi: 10.1158/1078-0432.CCR-21-0023. Epub 2021 Mar 4. Clin Cancer Res. 2021. PMID: 33664059 Free PMC article.
Role of SLC transporters in toxicity induced by anticancer drugs.
Huang KM, Uddin ME, DiGiacomo D, Lustberg MB, Hu S, Sparreboom A. Huang KM, et al. Expert Opin Drug Metab Toxicol. 2020 Jun;16(6):493-506. doi: 10.1080/17425255.2020.1755253. Epub 2020 Apr 26. Expert Opin Drug Metab Toxicol. 2020. PMID: 32276560 Free PMC article. Review.
24 results