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Palmitoylation couples insulin hypersecretion with β cell failure in diabetes.
Dong G, Adak S, Spyropoulos G, Zhang Q, Feng C, Yin L, Speck SL, Shyr Z, Morikawa S, Kitamura RA, Kathayat RS, Dickinson BC, Ng XW, Piston DW, Urano F, Remedi MS, Wei X, Semenkovich CF. Dong G, et al. Cell Metab. 2023 Feb 7;35(2):332-344.e7. doi: 10.1016/j.cmet.2022.12.012. Epub 2023 Jan 11. Cell Metab. 2023. PMID: 36634673 Free PMC article.
A phase Ib/IIa clinical trial of dantrolene sodium in patients with Wolfram syndrome.
Abreu D, Stone SI, Pearson TS, Bucelli RC, Simpson AN, Hurst S, Brown CM, Kries K, Onwumere C, Gu H, Hoekel J, Tychsen L, Van Stavern GP, White NH, Marshall BA, Hershey T, Urano F. Abreu D, et al. JCI Insight. 2021 Aug 9;6(15):e145188. doi: 10.1172/jci.insight.145188. JCI Insight. 2021. PMID: 34185708 Free PMC article. Clinical Trial.
Neuroplastin Modulates Anti-inflammatory Effects of MANF.
Yagi T, Asada R, Kanekura K, Eesmaa A, Lindahl M, Saarma M, Urano F. Yagi T, et al. iScience. 2020 Nov 17;23(12):101810. doi: 10.1016/j.isci.2020.101810. eCollection 2020 Dec 18. iScience. 2020. PMID: 33299977 Free PMC article.
Current Landscape of Treatments for Wolfram Syndrome.
Abreu D, Urano F. Abreu D, et al. Trends Pharmacol Sci. 2019 Oct;40(10):711-714. doi: 10.1016/j.tips.2019.07.011. Epub 2019 Aug 13. Trends Pharmacol Sci. 2019. PMID: 31420094 Free PMC article. Review.
21 results