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Uncoupling protein-2 up-regulation and enhanced cyanide toxicity are mediated by PPARalpha activation and oxidative stress.
Toxicol Appl Pharmacol. 2007 Aug 15;223(1):10-9. doi: 10.1016/j.taap.2007.05.002. Epub 2007 May 18.
Toxicol Appl Pharmacol. 2007.
PMID: 17573087
Free PMC article.
HIF-1alpha activation by a redox-sensitive pathway mediates cyanide-induced BNIP3 upregulation and mitochondrial-dependent cell death.
Zhang L, Li L, Liu H, Prabhakaran K, Zhang X, Borowitz JL, Isom GE.
Zhang L, et al.
Free Radic Biol Med. 2007 Jul 1;43(1):117-27. doi: 10.1016/j.freeradbiomed.2007.04.005. Epub 2007 Apr 10.
Free Radic Biol Med. 2007.
PMID: 17561100
Free PMC article.
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Upregulation of BNIP3 and translocation to mitochondria mediates cyanide-induced apoptosis in cortical cells.
Prabhakaran K, Li L, Zhang L, Borowitz JL, Isom GE.
Prabhakaran K, et al.
Neuroscience. 2007 Nov 30;150(1):159-67. doi: 10.1016/j.neuroscience.2007.07.033. Epub 2007 Jul 29.
Neuroscience. 2007.
PMID: 17980495
Free PMC article.
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