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Year Number of Results
2015 3
2016 4
2017 6
2018 2
2019 6
2020 2
2022 1
2024 0

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22 results

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Page 1
A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity.
Khan S, Zhang X, Lv D, Zhang Q, He Y, Zhang P, Liu X, Thummuri D, Yuan Y, Wiegand JS, Pei J, Zhang W, Sharma A, McCurdy CR, Kuruvilla VM, Baran N, Ferrando AA, Kim YM, Rogojina A, Houghton PJ, Huang G, Hromas R, Konopleva M, Zheng G, Zhou D. Khan S, et al. Nat Med. 2019 Dec;25(12):1938-1947. doi: 10.1038/s41591-019-0668-z. Epub 2019 Dec 2. Nat Med. 2019. PMID: 31792461 Free PMC article.
Interaction between APC and Fen1 during breast carcinogenesis.
Narayan S, Jaiswal AS, Law BK, Kamal MA, Sharma AK, Hromas RA. Narayan S, et al. DNA Repair (Amst). 2016 May;41:54-62. doi: 10.1016/j.dnarep.2016.04.003. Epub 2016 Apr 7. DNA Repair (Amst). 2016. PMID: 27088617 Free PMC article. Review.
Drugging the Cancers Addicted to DNA Repair.
Nickoloff JA, Jones D, Lee SH, Williamson EA, Hromas R. Nickoloff JA, et al. J Natl Cancer Inst. 2017 Nov 1;109(11):djx059. doi: 10.1093/jnci/djx059. J Natl Cancer Inst. 2017. PMID: 28521333 Free PMC article. Review.
Synthetic lethality in malignant pleural mesothelioma with PARP1 inhibition.
Srinivasan G, Sidhu GS, Williamson EA, Jaiswal AS, Najmunnisa N, Wilcoxen K, Jones D, George TJ Jr, Hromas R. Srinivasan G, et al. Cancer Chemother Pharmacol. 2017 Oct;80(4):861-867. doi: 10.1007/s00280-017-3401-y. Epub 2017 Jul 29. Cancer Chemother Pharmacol. 2017. PMID: 28756516 Free PMC article.
The splicing component ISY1 regulates APE1 in base excision repair.
Jaiswal AS, Williamson EA, Srinivasan G, Kong K, Lomelino CL, McKenna R, Walter C, Sung P, Narayan S, Hromas R. Jaiswal AS, et al. DNA Repair (Amst). 2020 Feb;86:102769. doi: 10.1016/j.dnarep.2019.102769. Epub 2019 Dec 13. DNA Repair (Amst). 2020. PMID: 31887540 Free PMC article.
MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers.
Srinivasan G, Williamson EA, Kong K, Jaiswal AS, Huang G, Kim HS, Schärer O, Zhao W, Burma S, Sung P, Hromas R. Srinivasan G, et al. Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17438-17443. doi: 10.1073/pnas.1903150116. Epub 2019 Aug 8. Proc Natl Acad Sci U S A. 2019. PMID: 31395736 Free PMC article.
BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1.
Hromas R, Srinivasan G, Yang M, Jaiswal A, Totterdale TA, Phillips L, Kirby A, Khodayari N, Brantley M, Williamson EA, Kong KY. Hromas R, et al. iScience. 2022 Nov 19;25(12):105626. doi: 10.1016/j.isci.2022.105626. eCollection 2022 Dec 22. iScience. 2022. PMID: 36471805 Free PMC article.
Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks.
Kim HS, Nickoloff JA, Wu Y, Williamson EA, Sidhu GS, Reinert BL, Jaiswal AS, Srinivasan G, Patel B, Kong K, Burma S, Lee SH, Hromas RA. Kim HS, et al. J Biol Chem. 2017 Feb 17;292(7):2795-2804. doi: 10.1074/jbc.M116.758235. Epub 2017 Jan 3. J Biol Chem. 2017. PMID: 28049724 Free PMC article.
22 results