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Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal.
Sun WY, Tyurin VA, Mikulska-Ruminska K, Shrivastava IH, Anthonymuthu TS, Zhai YJ, Pan MH, Gong HB, Lu DH, Sun J, Duan WJ, Korolev S, Abramov AY, Angelova PR, Miller I, Beharier O, Mao GW, Dar HH, Kapralov AA, Amoscato AA, Hastings TG, Greenamyre TJ, Chu CT, Sadovsky Y, Bahar I, Bayır H, Tyurina YY, He RR, Kagan VE. Sun WY, et al. Nat Chem Biol. 2021 Apr;17(4):465-476. doi: 10.1038/s41589-020-00734-x. Epub 2021 Feb 4. Nat Chem Biol. 2021. PMID: 33542532 Free PMC article.
Achieving Life through Death: Redox Biology of Lipid Peroxidation in Ferroptosis.
Bayır H, Anthonymuthu TS, Tyurina YY, Patel SJ, Amoscato AA, Lamade AM, Yang Q, Vladimirov GK, Philpott CC, Kagan VE. Bayır H, et al. Cell Chem Biol. 2020 Apr 16;27(4):387-408. doi: 10.1016/j.chembiol.2020.03.014. Epub 2020 Apr 9. Cell Chem Biol. 2020. PMID: 32275865 Free PMC article. Review.
Mitochondrial damage & lipid signaling in traumatic brain injury.
Lamade AM, Anthonymuthu TS, Hier ZE, Gao Y, Kagan VE, Bayır H. Lamade AM, et al. Exp Neurol. 2020 Jul;329:113307. doi: 10.1016/j.expneurol.2020.113307. Epub 2020 Apr 11. Exp Neurol. 2020. PMID: 32289317 Free PMC article. Review.
"Redox lipidomics technology: Looking for a needle in a haystack".
Tyurina YY, Tyurin VA, Anthonymuthu T, Amoscato AA, Sparvero LJ, Nesterova AM, Baynard ML, Sun W, He R, Khaitovich P, Vladimirov YA, Gabrilovich DI, Bayır H, Kagan VE. Tyurina YY, et al. Chem Phys Lipids. 2019 Jul;221:93-107. doi: 10.1016/j.chemphyslip.2019.03.012. Epub 2019 Mar 27. Chem Phys Lipids. 2019. PMID: 30928338 Free PMC article. Review.
Redox phospholipidomics of enzymatically generated oxygenated phospholipids as specific signals of programmed cell death.
Kagan VE, Tyurina YY, Sun WY, Vlasova II, Dar H, Tyurin VA, Amoscato AA, Mallampalli R, van der Wel PCA, He RR, Shvedova AA, Gabrilovich DI, Bayir H. Kagan VE, et al. Free Radic Biol Med. 2020 Feb 1;147:231-241. doi: 10.1016/j.freeradbiomed.2019.12.028. Epub 2019 Dec 25. Free Radic Biol Med. 2020. PMID: 31883467 Free PMC article. Review.
Iron catalysis of lipid peroxidation in ferroptosis: Regulated enzymatic or random free radical reaction?
Stoyanovsky DA, Tyurina YY, Shrivastava I, Bahar I, Tyurin VA, Protchenko O, Jadhav S, Bolevich SB, Kozlov AV, Vladimirov YA, Shvedova AA, Philpott CC, Bayir H, Kagan VE. Stoyanovsky DA, et al. Free Radic Biol Med. 2019 Mar;133:153-161. doi: 10.1016/j.freeradbiomed.2018.09.008. Epub 2018 Sep 12. Free Radic Biol Med. 2019. PMID: 30217775 Free PMC article. Review.
21 results