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The Arg59Trp variant in ANGPTL8 (betatrophin) is associated with total and HDL-cholesterol in American Indians and Mexican Americans and differentially affects cleavage of ANGPTL3.
Mol Genet Metab. 2016 Jun;118(2):128-37. doi: 10.1016/j.ymgme.2016.04.007. Epub 2016 Apr 19.
Mol Genet Metab. 2016.
PMID: 27117576
Free PMC article.
MicroRNA-27a decreases the level and efficiency of the LDL receptor and contributes to the dysregulation of cholesterol homeostasis.
Alvarez ML, Khosroheidari M, Eddy E, Done SC.
Alvarez ML, et al.
Atherosclerosis. 2015 Oct;242(2):595-604. doi: 10.1016/j.atherosclerosis.2015.08.023. Epub 2015 Aug 20.
Atherosclerosis. 2015.
PMID: 26318398
Free PMC article.
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