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HOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growth.
Queisser MA, Dada LA, Deiss-Yehiely N, Angulo M, Zhou G, Kouri FM, Knab LM, Liu J, Stegh AH, DeCamp MM, Budinger GR, Chandel NS, Ciechanover A, Iwai K, Sznajder JI. Queisser MA, et al. Am J Respir Crit Care Med. 2014 Sep 15;190(6):688-98. doi: 10.1164/rccm.201403-0463OC. Am J Respir Crit Care Med. 2014. PMID: 25118570 Free PMC article.
Epithelial cell-specific loss of function of Miz1 causes a spontaneous COPD-like phenotype and up-regulates Ace2 expression in mice.
Do-Umehara HC, Chen C, Zhang Q, Misharin AV, Abdala-Valencia H, Casalino-Matsuda SM, Reyfman PA, Anekalla KR, Gonzalez-Gonzalez FJ, Sala MA, Peng C, Wu P, Wong CCL, Kalhan R, Bharat A, Perlman H, Ridge KM, Sznajder JI, Sporn PHS, Chandel NS, Yu J, Fu X, Petrache I, Tuder R, Budinger GRS, Liu J. Do-Umehara HC, et al. Sci Adv. 2020 Aug 14;6(33):eabb7238. doi: 10.1126/sciadv.abb7238. eCollection 2020 Aug. Sci Adv. 2020. PMID: 32851183 Free PMC article.