R01 NS064247/NS/NINDS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2010	1
2011	3
2012	2
2013	4
2014	3
2015	1
2024	0

1

APOE-modulated Aβ-induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective.

Tai LM, Ghura S, Koster KP, Liakaite V, Maienschein-Cline M, Kanabar P, Collins N, Ben-Aissa M, Lei AZ, Bahroos N, Green SJ, Hendrickson B, Van Eldik LJ, LaDu MJ. Tai LM, et al. J Neurochem. 2015 May;133(4):465-88. doi: 10.1111/jnc.13072. Epub 2015 Mar 18. J Neurochem. 2015. PMID: 25689586 Free PMC article. Review.

2

Diffuse brain injury induces acute post-traumatic sleep.

Rowe RK, Striz M, Bachstetter AD, Van Eldik LJ, Donohue KD, O'Hara BF, Lifshitz J. Rowe RK, et al. PLoS One. 2014 Jan 8;9(1):e82507. doi: 10.1371/journal.pone.0082507. eCollection 2014. PLoS One. 2014. PMID: 24416145 Free PMC article.

3

Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model of Alzheimer's disease.

Webster SJ, Bachstetter AD, Van Eldik LJ. Webster SJ, et al. Alzheimers Res Ther. 2013 May 24;5(3):28. doi: 10.1186/alzrt182. eCollection 2013. Alzheimers Res Ther. 2013. PMID: 23705774 Free PMC article.

4

Target engagement analysis and link to pharmacodynamic endpoint for a novel class of CNS-penetrant and efficacious p38α MAPK inhibitors.

Bachstetter AD, Watterson DM, Van Eldik LJ. Bachstetter AD, et al. J Neuroimmune Pharmacol. 2014 Sep;9(4):454-60. doi: 10.1007/s11481-014-9543-3. Epub 2014 May 1. J Neuroimmune Pharmacol. 2014. PMID: 24789302 Free PMC article.

5

Deficiency in p38β MAPK fails to inhibit cytokine production or protect neurons against inflammatory insult in in vitro and in vivo mouse models.

Xing B, Bachstetter AD, Van Eldik LJ. Xing B, et al. PLoS One. 2013;8(2):e56852. doi: 10.1371/journal.pone.0056852. Epub 2013 Feb 15. PLoS One. 2013. PMID: 23457629 Free PMC article.

6

The p38 MAP Kinase Family as Regulators of Proinflammatory Cytokine Production in Degenerative Diseases of the CNS.

Bachstetter AD, Van Eldik LJ. Bachstetter AD, et al. Aging Dis. 2010 Dec;1(3):199-211. Epub 2010 Sep 24. Aging Dis. 2010. PMID: 22720195 Free PMC article.

7

Microglial p38α MAPK is critical for LPS-induced neuron degeneration, through a mechanism involving TNFα.

Xing B, Bachstetter AD, Van Eldik LJ. Xing B, et al. Mol Neurodegener. 2011 Dec 20;6:84. doi: 10.1186/1750-1326-6-84. Mol Neurodegener. 2011. PMID: 22185458 Free PMC article.

8

Development of Novel In Vivo Chemical Probes to Address CNS Protein Kinase Involvement in Synaptic Dysfunction.

Watterson DM, Grum-Tokars VL, Roy SM, Schavocky JP, Bradaric BD, Bachstetter AD, Xing B, Dimayuga E, Saeed F, Zhang H, Staniszewski A, Pelletier JC, Minasov G, Anderson WF, Arancio O, Van Eldik LJ. Watterson DM, et al. PLoS One. 2013 Jun 26;8(6):e66226. doi: 10.1371/journal.pone.0066226. Print 2013. PLoS One. 2013. PMID: 23840427 Free PMC article.

9

The p38α MAPK regulates microglial responsiveness to diffuse traumatic brain injury.

Bachstetter AD, Rowe RK, Kaneko M, Goulding D, Lifshitz J, Van Eldik LJ. Bachstetter AD, et al. J Neurosci. 2013 Apr 3;33(14):6143-53. doi: 10.1523/JNEUROSCI.5399-12.2013. J Neurosci. 2013. PMID: 23554495 Free PMC article.

10

Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ).

Bachstetter AD, Xing B, de Almeida L, Dimayuga ER, Watterson DM, Van Eldik LJ. Bachstetter AD, et al. J Neuroinflammation. 2011 Jul 6;8:79. doi: 10.1186/1742-2094-8-79. J Neuroinflammation. 2011. PMID: 21733175 Free PMC article.

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