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Mutant Huntingtin Is Cleared from the Brain via Active Mechanisms in Huntington Disease.
J Neurosci. 2021 Jan 27;41(4):780-796. doi: 10.1523/JNEUROSCI.1865-20.2020. Epub 2020 Dec 11.
J Neurosci. 2021.
PMID: 33310753
Free PMC article.
Cerebrospinal fluid mutant huntingtin is a biomarker for huntingtin lowering in the striatum of Huntington disease mice.
Caron NS, Banos R, Aly AE, Xie Y, Ko S, Potluri N, Anderson C, Black HF, Anderson LM, Gordon B, Southwell AL, Hayden MR.
Caron NS, et al.
Neurobiol Dis. 2022 May;166:105652. doi: 10.1016/j.nbd.2022.105652. Epub 2022 Feb 7.
Neurobiol Dis. 2022.
PMID: 35143966
Free PMC article.
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