R01DK088133/DK/NIDDK NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2011	2
2012	2
2013	4
2014	4
2015	4
2024	0

1

Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms.

Gahete MD, Córdoba-Chacón J, Lin Q, Brüning JC, Kahn CR, Castaño JP, Christian H, Luque RM, Kineman RD. Gahete MD, et al. Endocrinology. 2013 Jul;154(7):2410-20. doi: 10.1210/en.2013-1261. Epub 2013 May 13. Endocrinology. 2013. PMID: 23671263 Free PMC article.

2

Homologous and heterologous in vitro regulation of pituitary receptors for somatostatin, growth hormone (GH)-releasing hormone, and ghrelin in a nonhuman primate (Papio anubis).

Córdoba-Chacón J, Gahete MD, Castaño JP, Kineman RD, Luque RM. Córdoba-Chacón J, et al. Endocrinology. 2012 Jan;153(1):264-72. doi: 10.1210/en.2011-1677. Epub 2011 Nov 22. Endocrinology. 2012. PMID: 22109886 Free PMC article.

3

Elevated GH/IGF-I promotes mammary tumors in high-fat, but not low-fat, fed mice.

Gahete MD, Córdoba-Chacón J, Lantvit DD, Ortega-Salas R, Sanchez-Sanchez R, Pérez-Jiménez F, López-Miranda J, Swanson SM, Castaño JP, Luque RM, Kineman RD. Gahete MD, et al. Carcinogenesis. 2014 Nov;35(11):2467-73. doi: 10.1093/carcin/bgu161. Epub 2014 Aug 1. Carcinogenesis. 2014. PMID: 25085903 Free PMC article.

4

Islet insulin content and release are increased in male mice with elevated endogenous GH and IGF-I, without evidence of systemic insulin resistance or alterations in β-cell mass.

Cordoba-Chacon J, Majumdar N, Pokala NK, Gahete MD, Kineman RD. Cordoba-Chacon J, et al. Growth Horm IGF Res. 2015 Aug;25(4):189-95. doi: 10.1016/j.ghir.2015.04.002. Epub 2015 Apr 17. Growth Horm IGF Res. 2015. PMID: 25936582

5

Endogenous somatostatin is critical in regulating the acute effects of L-arginine on growth hormone and insulin release in mice.

Córdoba-Chacón J, Gahete MD, Pozo-Salas AI, Castaño JP, Kineman RD, Luque RM. Córdoba-Chacón J, et al. Endocrinology. 2013 Jul;154(7):2393-8. doi: 10.1210/en.2013-1136. Epub 2013 May 21. Endocrinology. 2013. PMID: 23696563 Free PMC article.

6

Melatonin regulates somatotrope and lactotrope function through common and distinct signaling pathways in cultured primary pituitary cells from female primates.

Ibáñez-Costa A, Córdoba-Chacón J, Gahete MD, Kineman RD, Castaño JP, Luque RM. Ibáñez-Costa A, et al. Endocrinology. 2015 Mar;156(3):1100-10. doi: 10.1210/en.2014-1819. Epub 2014 Dec 29. Endocrinology. 2015. PMID: 25545385 Free PMC article.

7

Truncated somatostatin receptor variant sst5TMD4 confers aggressive features (proliferation, invasion and reduced octreotide response) to somatotropinomas.

Luque RM, Ibáñez-Costa A, Neto LV, Taboada GF, Hormaechea-Agulla D, Kasuki L, Venegas-Moreno E, Moreno-Carazo A, Gálvez MÁ, Soto-Moreno A, Kineman RD, Culler MD, Gahete MD, Gadelha MR, Castaño JP. Luque RM, et al. Cancer Lett. 2015 Apr 10;359(2):299-306. doi: 10.1016/j.canlet.2015.01.037. Epub 2015 Jan 28. Cancer Lett. 2015. PMID: 25637790 Free PMC article.

8

Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice.

Cordoba-Chacon J, Majumdar N, List EO, Diaz-Ruiz A, Frank SJ, Manzano A, Bartrons R, Puchowicz M, Kopchick JJ, Kineman RD. Cordoba-Chacon J, et al. Diabetes. 2015 Sep;64(9):3093-103. doi: 10.2337/db15-0370. Epub 2015 May 26. Diabetes. 2015. PMID: 26015548 Free PMC article.

9

Long- but not short-term adult-onset, isolated GH deficiency in male mice leads to deterioration of β-cell function, which cannot be accounted for by changes in β-cell mass.

Cordoba-Chacon J, Gahete MD, Pokala NK, Geldermann D, Alba M, Salvatori R, Luque RM, Kineman RD. Cordoba-Chacon J, et al. Endocrinology. 2014 Mar;155(3):726-35. doi: 10.1210/en.2013-1825. Epub 2013 Dec 16. Endocrinology. 2014. PMID: 24424062 Free PMC article.

10

Elevated GH/IGF-I, due to somatotrope-specific loss of both IGF-I and insulin receptors, alters glucose homeostasis and insulin sensitivity in a diet-dependent manner.

Gahete MD, Córdoba-Chacón J, Anadumaka CV, Lin Q, Brüning JC, Kahn CR, Luque RM, Kineman RD. Gahete MD, et al. Endocrinology. 2011 Dec;152(12):4825-37. doi: 10.1210/en.2011-1447. Epub 2011 Oct 11. Endocrinology. 2011. PMID: 21990313 Free PMC article.

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