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2013 | 2 |
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The SIX1-EYA transcriptional complex as a therapeutic target in cancer.
Expert Opin Ther Targets. 2015 Feb;19(2):213-25. doi: 10.1517/14728222.2014.978860. Epub 2015 Jan 2.
Expert Opin Ther Targets. 2015.
PMID: 25555392
Free PMC article.
Review.
The Eya phosphatase: Its unique role in cancer.
Zhou H, Zhang L, Vartuli RL, Ford HL, Zhao R.
Zhou H, et al.
Int J Biochem Cell Biol. 2018 Mar;96:165-170. doi: 10.1016/j.biocel.2017.09.001. Epub 2017 Sep 5.
Int J Biochem Cell Biol. 2018.
PMID: 28887153
Free PMC article.
Review.
Item in Clipboard
In Vitro Phosphatase Assays for the Eya2 Tyrosine Phosphatase.
Alderman C, Krueger A, Rossi J, Ford HL, Zhao R.
Alderman C, et al.
Methods Mol Biol. 2024;2743:285-300. doi: 10.1007/978-1-0716-3569-8_18.
Methods Mol Biol. 2024.
PMID: 38147222
Free PMC article.
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Identification of a selective small-molecule inhibitor series targeting the eyes absent 2 (Eya2) phosphatase activity.
Krueger AB, Dehdashti SJ, Southall N, Marugan JJ, Ferrer M, Li X, Ford HL, Zheng W, Zhao R.
Krueger AB, et al.
J Biomol Screen. 2013 Jan;18(1):85-96. doi: 10.1177/1087057112453936. Epub 2012 Jul 20.
J Biomol Screen. 2013.
PMID: 22820394
Free PMC article.
Item in Clipboard
Structural and Functional Analyses of an Allosteric EYA2 Phosphatase Inhibitor That Has On-Target Effects in Human Lung Cancer Cells.
Anantharajan J, Zhou H, Zhang L, Hotz T, Vincent MY, Blevins MA, Jansson AE, Kuan JWL, Ng EY, Yeo YK, Baburajendran N, Lin G, Hung AW, Joy J, Patnaik S, Marugan J, Rudra P, Ghosh D, Hill J, Keller TH, Zhao R, Ford HL, Kang C.
Anantharajan J, et al.
Mol Cancer Ther. 2019 Sep;18(9):1484-1496. doi: 10.1158/1535-7163.MCT-18-1239. Epub 2019 Jul 8.
Mol Cancer Ther. 2019.
PMID: 31285279
Free PMC article.
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Structure-function analyses of the human SIX1-EYA2 complex reveal insights into metastasis and BOR syndrome.
Patrick AN, Cabrera JH, Smith AL, Chen XS, Ford HL, Zhao R.
Patrick AN, et al.
Nat Struct Mol Biol. 2013 Apr;20(4):447-53. doi: 10.1038/nsmb.2505. Epub 2013 Feb 24.
Nat Struct Mol Biol. 2013.
PMID: 23435380
Free PMC article.
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Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.
Krueger AB, Drasin DJ, Lea WA, Patrick AN, Patnaik S, Backos DS, Matheson CJ, Hu X, Barnaeva E, Holliday MJ, Blevins MA, Robin TP, Eisenmesser EZ, Ferrer M, Simeonov A, Southall N, Reigan P, Marugan J, Ford HL, Zhao R.
Krueger AB, et al.
J Biol Chem. 2014 Jun 6;289(23):16349-61. doi: 10.1074/jbc.M114.566729. Epub 2014 Apr 22.
J Biol Chem. 2014.
PMID: 24755226
Free PMC article.
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