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Page 1
Regulation of Drug Transport Proteins-From Mechanisms to Clinical Impact: A White Paper on Behalf of the International Transporter Consortium.
Brouwer KLR, Evers R, Hayden E, Hu S, Li CY, Meyer Zu Schwabedissen HE, Neuhoff S, Oswald S, Piquette-Miller M, Saran C, Sjöstedt N, Sprowl JA, Stahl SH, Yue W. Brouwer KLR, et al. Clin Pharmacol Ther. 2022 Sep;112(3):461-484. doi: 10.1002/cpt.2605. Epub 2022 May 24. Clin Pharmacol Ther. 2022. PMID: 35390174 Free PMC article. Review.
Intestinal P-gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications.
Zamek-Gliszczynski MJ, Patel M, Yang X, Lutz JD, Chu X, Brouwer KLR, Lai Y, Lee CA, Neuhoff S, Paine MF, Sugiyama Y, Taskar KS, Galetin A. Zamek-Gliszczynski MJ, et al. Clin Pharmacol Ther. 2021 Jan;109(1):55-64. doi: 10.1002/cpt.1916. Epub 2020 Jul 9. Clin Pharmacol Ther. 2021. PMID: 32460379 Free PMC article. Review.
Cefazolin pharmacokinetics in premature infants.
Balevic SJ, Smith PB, Testoni D, Wu H, Brouwer KLR, Zimmerman KO, Rivera-Chaparro ND, Benjamin DK Jr, Cohen-Wolkowiez M. Balevic SJ, et al. J Perinatol. 2019 Sep;39(9):1213-1218. doi: 10.1038/s41372-019-0368-z. Epub 2019 Apr 3. J Perinatol. 2019. PMID: 30944398 Free PMC article.
In vitro to in vivo extrapolation for high throughput prioritization and decision making.
Bell SM, Chang X, Wambaugh JF, Allen DG, Bartels M, Brouwer KLR, Casey WM, Choksi N, Ferguson SS, Fraczkiewicz G, Jarabek AM, Ke A, Lumen A, Lynn SG, Paini A, Price PS, Ring C, Simon TW, Sipes NS, Sprankle CS, Strickland J, Troutman J, Wetmore BA, Kleinstreuer NC. Bell SM, et al. Toxicol In Vitro. 2018 Mar;47:213-227. doi: 10.1016/j.tiv.2017.11.016. Epub 2017 Dec 5. Toxicol In Vitro. 2018. PMID: 29203341 Free PMC article. Review.
51 results