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Categorization of lung mesenchymal cells in development and fibrosis.
Liu X, Rowan SC, Liang J, Yao C, Huang G, Deng N, Xie T, Wu D, Wang Y, Burman A, Parimon T, Borok Z, Chen P, Parks WC, Hogaboam CM, Weigt SS, Belperio J, Stripp BR, Noble PW, Jiang D. Liu X, et al. iScience. 2021 May 19;24(6):102551. doi: 10.1016/j.isci.2021.102551. eCollection 2021 Jun 25. iScience. 2021. PMID: 34151224 Free PMC article.
Antibody-mediated depletion of CCR10+EphA3+ cells ameliorates fibrosis in IPF.
Hohmann MS, Habiel DM, Espindola MS, Huang G, Jones I, Narayanan R, Coelho AL, Oldham JM, Noth I, Ma SF, Kurkciyan A, McQualter JL, Carraro G, Stripp B, Chen P, Jiang D, Noble PW, Parks W, Woronicz J, Yarranton G, Murray LA, Hogaboam CM. Hohmann MS, et al. JCI Insight. 2021 Jun 8;6(11):e141061. doi: 10.1172/jci.insight.141061. JCI Insight. 2021. PMID: 33945505 Free PMC article.
Caveolin scaffolding domain (CSD) peptide LTI-2355 modulates the phagocytic and synthetic activity of lung derived myeloid cells in Idiopathic Pulmonary Fibrosis (IPF) and Post-acute sequelae of COVID-fibrosis (PASC-F).
Creyns B, MacKenzie B, Sa Y, Coelho AL, Christensen D, Parimon T, Windsor B, Hogaboam CM. Creyns B, et al. bioRxiv [Preprint]. 2024 Jan 16:2023.12.01.569608. doi: 10.1101/2023.12.01.569608. bioRxiv. 2024. PMID: 38654821 Free PMC article. Preprint.
Pre-clinical proof-of-concept of anti-fibrotic activity of caveolin-1 scaffolding domain peptide LTI-03 in ex vivo precision cut lung slices from patients with Idiopathic Pulmonary Fibrosis.
MacKenzie B, Mahavadi P, Jannini-Sa YAP, Creyns B, Coelho AL, Espindola M, Ruppert C, Hötzenecker K, Hogaboam C, Guenther A. MacKenzie B, et al. bioRxiv [Preprint]. 2024 Apr 28:2024.04.24.589970. doi: 10.1101/2024.04.24.589970. bioRxiv. 2024. PMID: 38712072 Free PMC article. Preprint.