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Elevated gadd153/chop expression and enhanced c-Jun N-terminal protein kinase activation sensitizes aged cells to ER stress.
Exp Gerontol. 2004 May;39(5):735-44. doi: 10.1016/j.exger.2004.02.008.
Exp Gerontol. 2004.
PMID: 15130668
Expression of the pro-apoptotic gene gadd153/chop is elevated in liver with aging and sensitizes cells to oxidant injury.
Ikeyama S, Wang XT, Li J, Podlutsky A, Martindale JL, Kokkonen G, van Huizen R, Gorospe M, Holbrook NJ.
Ikeyama S, et al.
J Biol Chem. 2003 May 9;278(19):16726-31. doi: 10.1074/jbc.M300677200. Epub 2003 Feb 27.
J Biol Chem. 2003.
PMID: 12609979
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