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UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis.
Nat Med. 2017 Dec;23(12):1454-1465. doi: 10.1038/nm.4429. Epub 2017 Nov 13.
Nat Med. 2017.
PMID: 29131158
Free PMC article.
A Non-invasive Method to Assess Hepatic Acetyl-CoA In Vivo.
Perry RJ, Peng L, Cline GW, Petersen KF, Shulman GI.
Perry RJ, et al.
Cell Metab. 2017 Mar 7;25(3):749-756. doi: 10.1016/j.cmet.2016.12.017. Epub 2017 Jan 19.
Cell Metab. 2017.
PMID: 28111213
Free PMC article.
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The human brain produces fructose from glucose.
Hwang JJ, Jiang L, Hamza M, Dai F, Belfort-DeAguiar R, Cline G, Rothman DL, Mason G, Sherwin RS.
Hwang JJ, et al.
JCI Insight. 2017 Feb 23;2(4):e90508. doi: 10.1172/jci.insight.90508.
JCI Insight. 2017.
PMID: 28239653
Free PMC article.
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Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes.
Sharabi K, Lin H, Tavares CDJ, Dominy JE, Camporez JP, Perry RJ, Schilling R, Rines AK, Lee J, Hickey M, Bennion M, Palmer M, Nag PP, Bittker JA, Perez J, Jedrychowski MP, Ozcan U, Gygi SP, Kamenecka TM, Shulman GI, Schreiber SL, Griffin PR, Puigserver P.
Sharabi K, et al.
Cell. 2017 Mar 23;169(1):148-160.e15. doi: 10.1016/j.cell.2017.03.001.
Cell. 2017.
PMID: 28340340
Free PMC article.
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Mechanism for leptin's acute insulin-independent effect to reverse diabetic ketoacidosis.
Perry RJ, Peng L, Abulizi A, Kennedy L, Cline GW, Shulman GI.
Perry RJ, et al.
J Clin Invest. 2017 Feb 1;127(2):657-669. doi: 10.1172/JCI88477. Epub 2017 Jan 23.
J Clin Invest. 2017.
PMID: 28112679
Free PMC article.
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Mitochondrial-Targeted Catalase Protects Against High-Fat Diet-Induced Muscle Insulin Resistance by Decreasing Intramuscular Lipid Accumulation.
Lee HY, Lee JS, Alves T, Ladiges W, Rabinovitch PS, Jurczak MJ, Choi CS, Shulman GI, Samuel VT.
Lee HY, et al.
Diabetes. 2017 Aug;66(8):2072-2081. doi: 10.2337/db16-1334. Epub 2017 May 5.
Diabetes. 2017.
PMID: 28476930
Free PMC article.
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