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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1967 1
1968 1
1971 1
1973 1
1974 1
1975 3
1976 3
1977 3
1978 1
1979 1
1980 2
1981 2
1983 2
1984 8
1985 7
1986 2
1987 4
1988 3
1989 6
1990 1
1991 3
1992 2
1993 2
1994 5
1995 5
1997 1
1998 2
1999 2
2000 2
2001 1
2003 2
2004 4
2005 1
2006 3
2007 3
2008 5
2009 2
2010 6
2011 4
2012 5
2013 4
2014 3
2015 8
2016 4
2017 14
2018 8
2019 9
2020 10
2021 11
2022 17
2023 9
2024 4

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196 results

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Page 1
21-Deoxycortisol is a Key Screening Marker for 21-Hydroxylase Deficiency.
Held PK, Bialk ER, Lasarev MR, Allen DB. Held PK, et al. J Pediatr. 2022 Mar;242:213-219.e1. doi: 10.1016/j.jpeds.2021.10.063. Epub 2021 Nov 13. J Pediatr. 2022. PMID: 34780778
OBJECTIVES: To assess whether 21-deoxycortisol (21deoxy) can be used to predict 21-hydroxylase deficiency (21OHD) in newborns and to evaluate the influence of gestational age and the timing of collection on 21deoxy concentrations. ...
OBJECTIVES: To assess whether 21-deoxycortisol (21deoxy) can be used to predict 21-hydroxylase deficiency (21OHD) in newborns …
Congenital Adrenal Hyperplasia: Time to Replace 17OHP with 21-Deoxycortisol.
Miller WL. Miller WL. Horm Res Paediatr. 2019;91(6):416-420. doi: 10.1159/000501396. Epub 2019 Aug 26. Horm Res Paediatr. 2019. PMID: 31450227 Free article. Review.
In 21OHD, some of the accumulated intra-adrenal 17OHP is converted to 21-deoxycortisol (21-deoxy) by 11beta-hydroxylase (CYP11B1); 21-deoxy is not elevated in premature infants or in other forms of CAH, and hence is a more specific marker for 21OHD. ...
In 21OHD, some of the accumulated intra-adrenal 17OHP is converted to 21-deoxycortisol (21-deoxy) by 11beta-hydroxylase (CYP11 …
Serum 21-Deoxycortisol for Diagnosis of Nonclassic Congenital Adrenal Hyperplasia in Women With Androgen Excess.
Ng JL, Lim EM, Zhang R, Beilby JP, Watts GF, Brown SJ, Stuckey BGA. Ng JL, et al. J Clin Endocrinol Metab. 2023 Nov 17;108(12):e1560-e1570. doi: 10.1210/clinem/dgad377. J Clin Endocrinol Metab. 2023. PMID: 37358001 Free PMC article.
Increasing use of liquid chromatography and tandem mass spectrometry (LC-MS/MS) necessitates revision of immunoassay-based criteria for NCCAH. Measurement of 21-deoxycortisol (21DF) may simplify the diagnosis of heterozygosity (HTZ), the presence of 1 affected CYP21 …
Increasing use of liquid chromatography and tandem mass spectrometry (LC-MS/MS) necessitates revision of immunoassay-based criteria for NCCA …
The High Relevance of 21-Deoxycortisol, (Androstenedione + 17alpha-Hydroxyprogesterone)/Cortisol, and 11-Deoxycortisol/17alpha-Hydroxyprogesterone for Newborn Screening of 21-Hydroxylase Deficiency.
Watanabe K, Tsuji-Hosokawa A, Hashimoto A, Konishi K, Ishige N, Yajima H, Sutani A, Nakatani H, Gau M, Takasawa K, Tajima T, Hasegawa T, Morio T, Kashimada K. Watanabe K, et al. J Clin Endocrinol Metab. 2022 Nov 25;107(12):3341-3352. doi: 10.1210/clinem/dgac521. J Clin Endocrinol Metab. 2022. PMID: 36071550
METHODS: Five steroids (17alpha-hydroxyprogesterone [17alphaOHP], 21-deoxycortisol [21DOF], 11-deoxycortisol [11DOF], androstenedione [4AD], and cortisol [F]) were included in the panel of LC-MS/MS. ...
METHODS: Five steroids (17alpha-hydroxyprogesterone [17alphaOHP], 21-deoxycortisol [21DOF], 11-deoxycortisol [11DOF], androste …
[21-Deoxycortisol].
Okatani Y. Okatani Y. Nihon Rinsho. 1995 Mar;53 Su Pt 2:444-7. Nihon Rinsho. 1995. PMID: 8753277 Review. Japanese. No abstract available.
[11-deoxycortisol and 21-deoxycortisol].
Okatani Y, Hayashi K. Okatani Y, et al. Nihon Rinsho. 1999 Dec;57 Suppl:129-33. Nihon Rinsho. 1999. PMID: 10778082 Review. Japanese. No abstract available.
Electroacupuncture May Inhibit Oxidative Stress of Premature Ovarian Failure Mice by Regulating Intestinal Microbiota.
Geng Z, Nie X, Ling L, Li B, Liu P, Yuan L, Zhang K, Liu T, Zhang B. Geng Z, et al. Oxid Med Cell Longev. 2022 Aug 30;2022:4362317. doi: 10.1155/2022/4362317. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 36082082 Free PMC article.
The serum levels of estrone (E1), estrogen (E2), estriol (E3), and 21-deoxycortisol (21D) were measured by the HPLC-MS/MS method. The concentrations of Fe(2+), superoxide dismutase (SOD), hydroxyl radical (.OH), glutathione (GSH), superoxide anion, and malondialdehy …
The serum levels of estrone (E1), estrogen (E2), estriol (E3), and 21-deoxycortisol (21D) were measured by the HPLC-MS/MS meth …
Best Practice for Identification of Classical 21-Hydroxylase Deficiency Should Include 21 Deoxycortisol Analysis with Appropriate Isomeric Steroid Separation.
Greaves RF, Kumar M, Mawad N, Francescon A, Le C, O'Connell M, Chi J, Pitt J. Greaves RF, et al. Int J Neonatal Screen. 2023 Oct 16;9(4):58. doi: 10.3390/ijns9040058. Int J Neonatal Screen. 2023. PMID: 37873849 Free PMC article.
There are mixed reports on the inclusion and use of 21 deoxycortisol (21DF) as the primary decision marker for classical 21-hydroxylase deficiency. ...
There are mixed reports on the inclusion and use of 21 deoxycortisol (21DF) as the primary decision marker for classical 21-hy …
Cell foundry with high product specificity and catalytic activity for 21-deoxycortisol biotransformation.
Xiong S, Wang Y, Yao M, Liu H, Zhou X, Xiao W, Yuan Y. Xiong S, et al. Microb Cell Fact. 2017 Jun 13;16(1):105. doi: 10.1186/s12934-017-0720-y. Microb Cell Fact. 2017. PMID: 28610588 Free PMC article.
BACKGROUND: 21-deoxycortisol (21-DF) is the key intermediate to manufacture pharmaceutical glucocorticoids. ...
BACKGROUND: 21-deoxycortisol (21-DF) is the key intermediate to manufacture pharmaceutical glucocorticoids. ...
Adrenal C11-oxy C(21) steroids contribute to the C11-oxy C(19) steroid pool via the backdoor pathway in the biosynthesis and metabolism of 21-deoxycortisol and 21-deoxycortisone.
Barnard L, Gent R, van Rooyen D, Swart AC. Barnard L, et al. J Steroid Biochem Mol Biol. 2017 Nov;174:86-95. doi: 10.1016/j.jsbmb.2017.07.034. Epub 2017 Jul 31. J Steroid Biochem Mol Biol. 2017. PMID: 28774496
21-Hydroxylase deficiency presents with increased levels of cytochrome P450 21-hydroxylase substrates, progesterone and 17alpha-hydroxyprogesterone, which have been implicated in the production of androgens via the backdoor pathway. This study shows the biosynthesis of C11-oxy C( …
21-Hydroxylase deficiency presents with increased levels of cytochrome P450 21-hydroxylase substrates, progesterone and 17alpha-hydroxyproge …
196 results