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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
2000 1
2001 1
2002 7
2003 4
2004 5
2005 2
2006 8
2007 14
2008 14
2009 8
2010 7
2011 8
2012 6
2013 5
2014 9
2015 6
2016 4
2017 4
2018 7
2019 6
2020 5
2021 5
2022 3
2023 2
2024 1

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131 results

Results by year

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Page 1
Antibiotic allergy.
Blumenthal KG, Peter JG, Trubiano JA, Phillips EJ. Blumenthal KG, et al. Lancet. 2019 Jan 12;393(10167):183-198. doi: 10.1016/S0140-6736(18)32218-9. Epub 2018 Dec 14. Lancet. 2019. PMID: 30558872 Free PMC article. Review.
Antiviral drug allergy.
Milpied-Homsi B, Moran EM, Phillips EJ. Milpied-Homsi B, et al. Immunol Allergy Clin North Am. 2014 Aug;34(3):645-62, ix. doi: 10.1016/j.iac.2014.04.011. Immunol Allergy Clin North Am. 2014. PMID: 25017682 Free PMC article. Review.
Antiviral drugs used to treat HIV and hepatitis C are common causes of delayed drug hypersensitivities for which many of the more severe reactions have been recently shown to be immunogenetically mediated such as abacavir hypersensitivity where HLA-B()57:01 is now u …
Antiviral drugs used to treat HIV and hepatitis C are common causes of delayed drug hypersensitivities for which many of the more severe rea …
Worldwide Prevalence of Antibiotic-Associated Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Systematic Review and Meta-analysis.
Lee EY, Knox C, Phillips EJ. Lee EY, et al. JAMA Dermatol. 2023 Apr 1;159(4):384-392. doi: 10.1001/jamadermatol.2022.6378. JAMA Dermatol. 2023. PMID: 36790777 Free PMC article.
DATA EXTRACTION AND SYNTHESIS: Two reviewers (E.Y.L. and C.K.) independently selected the studies, extracted the data, and assessed the risk of bias. A meta-analysis using a random-effects model was performed in the studies that described patient-level associations. ...
DATA EXTRACTION AND SYNTHESIS: Two reviewers (E.Y.L. and C.K.) independently selected the studies, extracted the data, and assessed the risk …
Pharmacogenetics of hypersensitivity drug reactions.
Negrini S, Becquemont L. Negrini S, et al. Therapie. 2017 Apr;72(2):231-243. doi: 10.1016/j.therap.2016.12.009. Epub 2017 Jan 3. Therapie. 2017. PMID: 28162244 Review.
Most notable examples include human leukocyte antigen (HLA)-B*57:01 allele and abacavir hypersensitivity syndrome or HLA-B*15:02 and HLA-B*58:01 alleles related to severe cutaneous reactions induced by carbamazepine and allopurinol, respectively. This review aims to …
Most notable examples include human leukocyte antigen (HLA)-B*57:01 allele and abacavir hypersensitivity syndrome or HLA-B*15: …
Pharmacogenomics of antimicrobial agents.
Aung AK, Haas DW, Hulgan T, Phillips EJ. Aung AK, et al. Pharmacogenomics. 2014;15(15):1903-30. doi: 10.2217/pgs.14.147. Pharmacogenomics. 2014. PMID: 25495412 Free PMC article. Review.
In the last two decades, understanding of pharmacogenomic factors that influence antimicrobial efficacy and toxicity has rapidly evolved, leading to translational success such as the routine use of HLA-B*57:01 screening to prevent abacavir hypersensitivity reactions …
In the last two decades, understanding of pharmacogenomic factors that influence antimicrobial efficacy and toxicity has rapidly evolved, le …
Pharmacogenomics of antiretrovirals.
Roca B. Roca B. Recent Pat Antiinfect Drug Discov. 2008 Jun;3(2):132-5. doi: 10.2174/157489108784746650. Recent Pat Antiinfect Drug Discov. 2008. PMID: 18673126 Review.
Increasing knowledge about genes implicated in pharmacokinetics, mode of action, efficacy, and toxicity of drugs has already provided relevant results for clinical practice, for example: The strong association of the abacavir hypersensitivity reaction with HL …
Increasing knowledge about genes implicated in pharmacokinetics, mode of action, efficacy, and toxicity of drugs has already provided releva …
Genotyping for severe drug hypersensitivity.
Karlin E, Phillips E. Karlin E, et al. Curr Allergy Asthma Rep. 2014 Mar;14(3):418. doi: 10.1007/s11882-013-0418-0. Curr Allergy Asthma Rep. 2014. PMID: 24429903 Free PMC article. Review.
Key examples have included the associations of HLA-B*15:02 and carbamazepine induced SJS/TEN in Southeast Asian populations and HLA-B*57:01 and abacavir hypersensitivity. HLA-B*57:01 screening to prevent abacavir hypersensitivity exemplifies a successf …
Key examples have included the associations of HLA-B*15:02 and carbamazepine induced SJS/TEN in Southeast Asian populations and HLA-B*57:01 …
Pharmacogenetics of drug hypersensitivity.
Phillips EJ, Mallal SA. Phillips EJ, et al. Pharmacogenomics. 2010 Jul;11(7):973-87. doi: 10.2217/pgs.10.77. Pharmacogenomics. 2010. PMID: 20602616 Free PMC article. Review.
Despite this, several hurdles exist in the translation of these associations into pharmacogenetic tests that could be routinely used in the clinical setting. HLA-B*5701 screening to prevent abacavir hypersensitivity syndrome is an example of a test now in wid …
Despite this, several hurdles exist in the translation of these associations into pharmacogenetic tests that could be routinely used in the …
Human leukocyte antigen-associated drug hypersensitivity.
Illing PT, Vivian JP, Purcell AW, Rossjohn J, McCluskey J. Illing PT, et al. Curr Opin Immunol. 2013 Feb;25(1):81-9. doi: 10.1016/j.coi.2012.10.002. Epub 2012 Nov 8. Curr Opin Immunol. 2013. PMID: 23141566 Review.
Although several models have been proposed to explain these associations, an underlying molecular basis has only recently been described. The associations between HLA-B*57:01 and abacavir hypersensitivity syndrome, and HLA-B*15:02 and carbamazepine-induced bullous s …
Although several models have been proposed to explain these associations, an underlying molecular basis has only recently been described. Th …
131 results