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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1954 1
1957 2
1966 3
1967 3
1968 3
1969 5
1970 3
1971 6
1972 6
1973 10
1974 16
1975 39
1976 34
1977 37
1978 40
1979 43
1980 33
1981 52
1982 61
1983 75
1984 73
1985 91
1986 100
1987 95
1988 108
1989 126
1990 157
1991 161
1992 176
1993 196
1994 193
1995 204
1996 224
1997 243
1998 260
1999 309
2000 352
2001 357
2002 341
2003 440
2004 503
2005 523
2006 514
2007 584
2008 645
2009 657
2010 718
2011 800
2012 802
2013 863
2014 908
2015 892
2016 867
2017 964
2018 1006
2019 1053
2020 1005
2021 957
2022 919
2023 768
2024 275

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18,912 results

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Page 1
Lactulose versus Polyethylene Glycol for Chronic Constipation.
Lee-Robichaud H, Thomas K, Morgan J, Nelson RL. Lee-Robichaud H, et al. Cochrane Database Syst Rev. 2010 Jul 7;(7):CD007570. doi: 10.1002/14651858.CD007570.pub2. Cochrane Database Syst Rev. 2010. PMID: 20614462 Review.
MAIN RESULTS: In the present meta-analysis, we considered for the first time all ten randomised controlled trials so far performed. The findings of our work indicate that Polyethylene glycol is better than lactulose in outcomes of stool frequency per week, form of stool, r …
MAIN RESULTS: In the present meta-analysis, we considered for the first time all ten randomised controlled trials so far performed. T …
Lactobacillus reuteri to Treat Infant Colic: A Meta-analysis.
Sung V, D'Amico F, Cabana MD, Chau K, Koren G, Savino F, Szajewska H, Deshpande G, Dupont C, Indrio F, Mentula S, Partty A, Tancredi D. Sung V, et al. Pediatrics. 2018 Jan;141(1):e20171811. doi: 10.1542/peds.2017-1811. Pediatrics. 2018. PMID: 29279326 Review.
DATA SOURCES: We searched online databases (PubMed, Medline, Embase, the Cumulative Index to Nursing and Allied Health Literature, the Database of Abstracts of Reviews of Effects, and Cochrane), e-abstracts, and clinical trial registries. STUDY SELECTION: These were …
DATA SOURCES: We searched online databases (PubMed, Medline, Embase, the Cumulative Index to Nursing and Allied Health Literature, the Datab …
Probiotics for Preventing and Treating Small Intestinal Bacterial Overgrowth: A Meta-Analysis and Systematic Review of Current Evidence.
Zhong C, Qu C, Wang B, Liang S, Zeng B. Zhong C, et al. J Clin Gastroenterol. 2017 Apr;51(4):300-311. doi: 10.1097/MCG.0000000000000814. J Clin Gastroenterol. 2017. PMID: 28267052 Review.
Also, the H2 concentration was significantly reduced among probiotic users (WMD=-36.35 ppm; 95% CI, -44.23 to -28.47 ppm; P<0.05). Although probiotics produced a marked decrease in the abdominal pain scores (WMD=-1.17; 95% CI, -2.30 to -0.04; P<0.05), it did n …
Also, the H2 concentration was significantly reduced among probiotic users (WMD=-36.35 ppm; 95% CI, -44.23 to -28.47 ppm; P<0.05). Althou …
Efficacy of psychological therapies for irritable bowel syndrome: systematic review and network meta-analysis.
Black CJ, Thakur ER, Houghton LA, Quigley EMM, Moayyedi P, Ford AC. Black CJ, et al. Gut. 2020 Aug;69(8):1441-1451. doi: 10.1136/gutjnl-2020-321191. Epub 2020 Apr 10. Gut. 2020. PMID: 32276950 Free article.
DESIGN: We searched the medical literature through January 2020 for randomised controlled trials (RCTs) assessing efficacy of psychological therapies for adults with IBS, compared with each other, or a control intervention. ...CBT-based interventions and gut-directed hypno …
DESIGN: We searched the medical literature through January 2020 for randomised controlled trials (RCTs) assessing efficacy of psychol …
Peppermint oil for the treatment of irritable bowel syndrome: a systematic review and meta-analysis.
Khanna R, MacDonald JK, Levesque BG. Khanna R, et al. J Clin Gastroenterol. 2014 Jul;48(6):505-12. doi: 10.1097/MCG.0b013e3182a88357. J Clin Gastroenterol. 2014. PMID: 24100754 Review.
Outcomes included global improvement of IBS symptoms, improvement in abdominal pain, and adverse events. Outcomes were analyzed using an intention-to-treat approach. ...Peppermint oil was found to be significantly superior to placebo for global improvement of IBS sy …
Outcomes included global improvement of IBS symptoms, improvement in abdominal pain, and adverse events. Outcomes were analyze …
Effectiveness and Safety of Probiotics for Patients with Constipation-Predominant Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of 10 Randomized Controlled Trials.
Shang X, E FF, Guo KL, Li YF, Zhao HL, Wang Y, Chen N, Nian T, Yang CQ, Yang KH, Li XX. Shang X, et al. Nutrients. 2022 Jun 15;14(12):2482. doi: 10.3390/nu14122482. Nutrients. 2022. PMID: 35745212 Free PMC article. Review.
RevMan 5.3 was used to perform a meta-analysis on stool consistency, abdominal pain, bloating, quality of life (QoL), fecal Bifidobacterium and Lactobacillus counts, and adverse events. ...The meta-analysis results show that, compared to the placebo, probiotics sign …
RevMan 5.3 was used to perform a meta-analysis on stool consistency, abdominal pain, bloating, quality of life (QoL), fecal Bi …
Physical activity for primary dysmenorrhea: a systematic review and meta-analysis of randomized controlled trials.
Matthewman G, Lee A, Kaur JG, Daley AJ. Matthewman G, et al. Am J Obstet Gynecol. 2018 Sep;219(3):255.e1-255.e20. doi: 10.1016/j.ajog.2018.04.001. Epub 2018 Apr 7. Am J Obstet Gynecol. 2018. PMID: 29630882
BACKGROUND: Primary dysmenorrhea is cramping abdominal pain associated with menses. It is prevalent, affects quality of life, and can cause absenteeism. ...Random effects meta-analyses for pain intensity and pain duration were conducted, with prespecified sub …
BACKGROUND: Primary dysmenorrhea is cramping abdominal pain associated with menses. It is prevalent, affects quality of life, …
Efficacy and safety of probiotics in the treatment of irritable bowel syndrome: A systematic review and meta-analysis of randomised clinical trials using ROME IV criteria.
Konstantis G, Efstathiou S, Pourzitaki C, Kitsikidou E, Germanidis G, Chourdakis M. Konstantis G, et al. Clin Nutr. 2023 May;42(5):800-809. doi: 10.1016/j.clnu.2023.03.019. Epub 2023 Mar 31. Clin Nutr. 2023. PMID: 37031468
Primary outcomes were the decrease of IBS-Symptom Severity Score (IBS-SSS) and decrease of abdominal pain. The secondary outcomes were the improvement in quality of life (QoL) and the decrease of bloating. ...No significant reduction in IBS-SSS (WMD -43.2, 95% CI -8 …
Primary outcomes were the decrease of IBS-Symptom Severity Score (IBS-SSS) and decrease of abdominal pain. The secondary outco …
Efficacy of Tenapanor in Treating Patients With Irritable Bowel Syndrome With Constipation: A 26-Week, Placebo-Controlled Phase 3 Trial (T3MPO-2).
Chey WD, Lembo AJ, Yang Y, Rosenbaum DP. Chey WD, et al. Am J Gastroenterol. 2021 Jun 1;116(6):1294-1303. doi: 10.14309/ajg.0000000000001056. Am J Gastroenterol. 2021. PMID: 33337659 Free PMC article. Clinical Trial.
METHODS: In this randomized double-blind study (ClinicalTrials.gov identifier: NCT02686138), patients with IBS-C received tenapanor 50 mg b.i.d. or placebo b.i.d. for 26 weeks. The primary endpoint was the proportion of patients who had a reduction of 30.0% in average week …
METHODS: In this randomized double-blind study (ClinicalTrials.gov identifier: NCT02686138), patients with IBS-C received tenapanor 5 …
Efficacy of drugs in chronic idiopathic constipation: a systematic review and network meta-analysis.
Luthra P, Camilleri M, Burr NE, Quigley EMM, Black CJ, Ford AC. Luthra P, et al. Lancet Gastroenterol Hepatol. 2019 Nov;4(11):831-844. doi: 10.1016/S2468-1253(19)30246-8. Epub 2019 Aug 29. Lancet Gastroenterol Hepatol. 2019. PMID: 31474542 Free article.
METHODS: We searched Medline, Embase, Embase Classic, and the Cochrane Central Register of Controlled Trials for randomised controlled trials published from inception to week 3 June, 2019, to identify randomised controlled trials assessing the efficacy of drugs (osm …
METHODS: We searched Medline, Embase, Embase Classic, and the Cochrane Central Register of Controlled Trials for randomised controlle …
18,912 results
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