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Page 1
Characterization of aberrant glycosylation associated with osteoarthritis based on integrated glycomics methods.
Yu H, Li M, Shu J, Dang L, Wu X, Wang Y, Wang X, Chang X, Bao X, Zhu B, Ren X, Chen W, Li Y. Yu H, et al. Arthritis Res Ther. 2023 Jun 12;25(1):102. doi: 10.1186/s13075-023-03084-w. Arthritis Res Ther. 2023. PMID: 37308935 Free PMC article.
BACKGROUND: Osteoarthritis (OA) is the most common form of arthritis, affecting millions of aging people. Investigation of abnormal glycosylation is essential for the understanding of pathological mechanisms of OA. ...Interestingly, the microheterogeneity of N-glyca …
BACKGROUND: Osteoarthritis (OA) is the most common form of arthritis, affecting millions of aging people. Investigation of abnormal …
How glycosylation aids tumor angiogenesis: An updated review.
Cheng WK, Oon CE. Cheng WK, et al. Biomed Pharmacother. 2018 Jul;103:1246-1252. doi: 10.1016/j.biopha.2018.04.119. Epub 2018 May 7. Biomed Pharmacother. 2018. PMID: 29864905 Review.
The tumor microenvironment produces altered glycans that contribute to cancer progression and aggressiveness. Abnormal glycosylation is widely observed in tumor angiogenesis. Despite many attempts to decipher the role of glycosylation in different aspects of …
The tumor microenvironment produces altered glycans that contribute to cancer progression and aggressiveness. Abnormal glycosylati …
Beyond glyco-proteomics-Understanding the role of genetics in cancer biomarkers.
DelaCourt A, Mehta A. DelaCourt A, et al. Adv Cancer Res. 2023;157:57-81. doi: 10.1016/bs.acr.2022.07.002. Epub 2022 Oct 1. Adv Cancer Res. 2023. PMID: 36725113
Aberrant glycosylation is a common theme in cancer, with dysregulated glycosylation driving tumor initiation and metastasis, and abnormal glycosylation can be detection both on the tissue surface and in serum. ...This concept has already been established in the dete …
Aberrant glycosylation is a common theme in cancer, with dysregulated glycosylation driving tumor initiation and metastasis, and abnormal …
Protein N-glycosylation aberrations and glycoproteomic network alterations in osteoarthritis and osteoarthritis with type 2 diabetes.
Luo Y, Wu Z, Chen S, Luo H, Mo X, Wang Y, Tang J. Luo Y, et al. Sci Rep. 2022 Apr 28;12(1):6977. doi: 10.1038/s41598-022-10996-1. Sci Rep. 2022. PMID: 35484284 Free PMC article.
Whether the relationship between type 2 diabetes mellitus (T2DM) and osteoarthritis (OA) can be solely attributed to the shared risk factors, such as obesity, remains controversial. Several studies have revealed the critical role of abnormal glycosylation in the pat …
Whether the relationship between type 2 diabetes mellitus (T2DM) and osteoarthritis (OA) can be solely attributed to the shared risk factors …
Abnormal B cell glycosylation in autoimmunity: A new potential treatment strategy.
Morel M, Pochard P, Echchih W, Dueymes M, Bagacean C, Jousse-Joulin S, Devauchelle-Pensec V, Cornec D, Jamin C, Pers JO, Bordron A. Morel M, et al. Front Immunol. 2022 Aug 25;13:975963. doi: 10.3389/fimmu.2022.975963. eCollection 2022. Front Immunol. 2022. PMID: 36091064 Free PMC article.
Both SLE T cell markers and pSS-associated autoantibodies exhibit abnormal glycosylation. Such dysregulation suggests that defective glycosylation may also occur in B cells, thereby modifying their behaviour and reactivity. ...Additionally, the SLE B lymphocytes had …
Both SLE T cell markers and pSS-associated autoantibodies exhibit abnormal glycosylation. Such dysregulation suggests that def …
Dysregulation and prometastatic function of glycosyltransferase C1GALT1 modulated by cHP1BP3/ miR-1-3p axis in bladder cancer.
Tan Z, Jiang Y, Liang L, Wu J, Cao L, Zhou X, Song Z, Ye Z, Zhao Z, Feng H, Dong Z, Lin S, Zhou Z, Wang Y, Li X, Guan F. Tan Z, et al. J Exp Clin Cancer Res. 2022 Jul 21;41(1):228. doi: 10.1186/s13046-022-02438-7. J Exp Clin Cancer Res. 2022. PMID: 35864552 Free PMC article.
BACKGROUND: Abnormal glycosylation in a variety of cancer types is involved in tumor progression and chemoresistance. ...Effects of miR-1-3p and cHP1BP3 (circRNA derived from HP1BP3) on modulating C1GALT1 expression were investigated by target prediction prog …
BACKGROUND: Abnormal glycosylation in a variety of cancer types is involved in tumor progression and chemoresistance. ...Effec …
Post-translational modifications in tumor biomarkers: the next challenge for aptamers?
Díaz-Fernández A, Miranda-Castro R, de-Los-Santos-Álvarez N, Lobo-Castañón MJ. Díaz-Fernández A, et al. Anal Bioanal Chem. 2018 Mar;410(8):2059-2065. doi: 10.1007/s00216-018-0861-9. Epub 2018 Jan 20. Anal Bioanal Chem. 2018. PMID: 29353432 Review.
In recent years, it has been reported that the pattern of post-translational modifications, altered under neoplastic disease, is a better predictive biomarker than the total protein level. Among others, abnormal glycosylation is attracting great attention. .. …
In recent years, it has been reported that the pattern of post-translational modifications, altered under neoplastic disease, is a better …
Construction of an abnormal glycosylation risk model and its application in predicting the prognosis of patients with head and neck cancer.
Gao Y, Li W, Guo H, Hao Y, Lu L, Li J, Piao S. Gao Y, et al. Sci Rep. 2024 Jan 15;14(1):1310. doi: 10.1038/s41598-023-50092-6. Sci Rep. 2024. PMID: 38225277 Free PMC article.
Multiple Cox Proportional Hazards Regression Model (Cox regression) and LASSO analysis were conducted to identify the key genes exhibiting the strongest association with prognosis. A risk score, known as the glycosylation-related genes risk score (GLRS), was subsequ …
Multiple Cox Proportional Hazards Regression Model (Cox regression) and LASSO analysis were conducted to identify the key genes exhibiting t …
Muscular dystrophies due to defective glycosylation of dystroglycan.
Muntoni F, Brockington M, Godfrey C, Ackroyd M, Robb S, Manzur A, Kinali M, Mercuri E, Kaluarachchi M, Feng L, Jimenez-Mallebrera C, Clement E, Torelli S, Sewry CA, Brown SC. Muntoni F, et al. Acta Myol. 2007 Dec;26(3):129-35. Acta Myol. 2007. PMID: 18646561 Free PMC article. Review.
In the last few years a novel and frequent pathogenic mechanism has been identified that involves the abnormal glycosylation of alpha-dystroglycan (ADG). This peripheral membrane protein undergoes complex and crucial glycosylation steps that enable it to interact wi …
In the last few years a novel and frequent pathogenic mechanism has been identified that involves the abnormal glycosylation o …
Host mucin glycosylation plays a role in bacterial adhesion in lungs of individuals with cystic fibrosis.
Venkatakrishnan V, Packer NH, Thaysen-Andersen M. Venkatakrishnan V, et al. Expert Rev Respir Med. 2013 Oct;7(5):553-76. doi: 10.1586/17476348.2013.837752. Expert Rev Respir Med. 2013. PMID: 24138697 Review.
Malfunction of the cell surface glycoprotein, cystic fibrosis transmembrane conductance regulator, is the molecular hallmark of cystic fibrosis (CF), causing salt imbalance across the lung epithelium and biochemical and biophysical alterations of the mucous secretion and airway s …
Malfunction of the cell surface glycoprotein, cystic fibrosis transmembrane conductance regulator, is the molecular hallmark of cystic fibro …
57 results