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Year Number of Results
1982 1
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1994 2
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281 results

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Quoted phrase not found in phrase index: "Abnormal keratinocyte morphology"
Page 1
Pathophysiology of psoriasis: A review.
Yamanaka K, Yamamoto O, Honda T. Yamanaka K, et al. J Dermatol. 2021 Jun;48(6):722-731. doi: 10.1111/1346-8138.15913. Epub 2021 Apr 22. J Dermatol. 2021. PMID: 33886133 Review.
Psoriasis is a complex chronic inflammatory skin disease caused by the dynamic interplay between multiple genetic risk foci, environmental risk factors, and excessive immunological abnormalities. Psoriasis affects approximately 2% of the population worldwide, and dramatic …
Psoriasis is a complex chronic inflammatory skin disease caused by the dynamic interplay between multiple genetic risk foci, environmental r …
The cardiometabolic conditions of psoriatic disease.
Toussirot E, Gallais-Sérézal I, Aubin F. Toussirot E, et al. Front Immunol. 2022 Sep 8;13:970371. doi: 10.3389/fimmu.2022.970371. eCollection 2022. Front Immunol. 2022. PMID: 36159785 Free PMC article. Review.
Psoriasis (PsO) and psoriatic arthritis (PsA), together known as psoriatic disease (PsD), are immune-mediated diseases with a chronic and relapsing course that affect the skin, the joints or both. The pathophysiology of PsO is complex and involves abnormal expression of …
Psoriasis (PsO) and psoriatic arthritis (PsA), together known as psoriatic disease (PsD), are immune-mediated diseases with a chronic and re …
Single-cell RNA-seq reveals abnormal differentiation of keratinocytes and increased inflammatory differentiated keratinocytes in atopic dermatitis.
Zhou J, Liang G, Liu L, Feng S, Zheng Z, Wu Y, Chen X, Li X, Wang L, Wang L, Song Z. Zhou J, et al. J Eur Acad Dermatol Venereol. 2023 Nov;37(11):2336-2348. doi: 10.1111/jdv.19256. Epub 2023 Jul 3. J Eur Acad Dermatol Venereol. 2023. PMID: 37326015
RESULTS: ScRNA-seq analysis was able to profile a total of 87,853 cells, with keratinocytes (KCs) in AD manifesting highly expressed keratinocyte activation and pro-inflammatory genes. ...In vitro, IL19 directly downregulated KRT10 and LOR in HaCaT cells and activat …
RESULTS: ScRNA-seq analysis was able to profile a total of 87,853 cells, with keratinocytes (KCs) in AD manifesting highly expressed …
Pustular psoriasis and related pustular skin diseases.
Bachelez H. Bachelez H. Br J Dermatol. 2018 Mar;178(3):614-618. doi: 10.1111/bjd.16232. Epub 2018 Jan 15. Br J Dermatol. 2018. PMID: 29333670 Review.
Patients with pustular psoriasis or related pustular diseases may have genetic abnormalities impairing the function of key players of the innate skin immune system. Recently, identification of these abnormalities has changed the paradigm of several of these diseases …
Patients with pustular psoriasis or related pustular diseases may have genetic abnormalities impairing the function of key players of …
Inherited ichthyoses/generalized Mendelian disorders of cornification.
Schmuth M, Martinz V, Janecke AR, Fauth C, Schossig A, Zschocke J, Gruber R. Schmuth M, et al. Eur J Hum Genet. 2013 Feb;21(2):123-33. doi: 10.1038/ejhg.2012.121. Epub 2012 Jun 27. Eur J Hum Genet. 2013. PMID: 22739337 Free PMC article. Review.
This etiologically and phenotypically heterogenous group of conditions is caused by mutations in various different genes important for keratinocyte differentiation and epidermal barrier function. Diagnosing a specific entity is a particular challenge for the nonspecialist …
This etiologically and phenotypically heterogenous group of conditions is caused by mutations in various different genes important for ke
Normal and abnormal skin color.
Ortonne JP. Ortonne JP. Ann Dermatol Venereol. 2012 Dec;139 Suppl 4:S125-9. doi: 10.1016/S0151-9638(12)70123-0. Ann Dermatol Venereol. 2012. PMID: 23522626 Review.
Hypermelanosis corresponds to an overload of melanin or an abnormal distribution of melanin in the skin. Depending on the color, melanodermia (brown/black) and ceruloderma (blue/grey) are distinguished. ...Finally, dyschromia can be related to the abnormal presence …
Hypermelanosis corresponds to an overload of melanin or an abnormal distribution of melanin in the skin. Depending on the color, mela …
Pediatric psoriasis: Understanding pathological conditions and advances in treatment.
Morita A, Saeki H. Morita A, et al. J Dermatol. 2024 Feb;51(2):185-195. doi: 10.1111/1346-8138.17049. Epub 2023 Dec 17. J Dermatol. 2024. PMID: 38105636 Review.
Pathologically, psoriasis is characterized by uncontrolled keratinocyte proliferation and abnormal differentiation, and histological features include acanthosis with inflammatory cell infiltration and neovascularization. ...
Pathologically, psoriasis is characterized by uncontrolled keratinocyte proliferation and abnormal differentiation, and histol …
Ichthyosis: A Road Model for Skin Research.
Vahlquist A, Törmä H. Vahlquist A, et al. Acta Derm Venereol. 2020 Mar 25;100(7):adv00097. doi: 10.2340/00015555-3433. Acta Derm Venereol. 2020. PMID: 32147743 Free PMC article. Review.
Studies of the aetiology of more than 50 types of ichthyosis have almost invariably uncovered errors in the biosynthesis of epidermal lipids or structural proteins essential for normal skin barrier function. The barrier abnormality per se may elicit epidermal inflammation, …
Studies of the aetiology of more than 50 types of ichthyosis have almost invariably uncovered errors in the biosynthesis of epidermal lipids …
Skin bioengineering: preclinical and clinical applications.
Martínez-Santamaría L, Guerrero-Aspizua S, Del Río M. Martínez-Santamaría L, et al. Actas Dermosifiliogr. 2012 Jan;103(1):5-11. doi: 10.1016/j.adengl.2011.03.016. Epub 2012 Mar 29. Actas Dermosifiliogr. 2012. PMID: 22464599 Free article. Review.
Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex.
Evtushenko NA, Beilin AK, Kosykh AV, Vorotelyak EA, Gurskaya NG. Evtushenko NA, et al. Int J Mol Sci. 2021 Nov 18;22(22):12446. doi: 10.3390/ijms222212446. Int J Mol Sci. 2021. PMID: 34830328 Free PMC article. Review.
The spectrum of changes initiated by phosphorylation includes the inhibition of proteasome degradation, TNF-alpha signaling activation, deregulated proliferation, abnormal cell migration, and impaired adherence of keratinocytes. ER stress also leads to the release o …
The spectrum of changes initiated by phosphorylation includes the inhibition of proteasome degradation, TNF-alpha signaling activation, dere …
281 results