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106 results

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Quoted phrase not found in phrase index: "Abnormal lymphatic vessel morphology"
Page 1
Genetic Basis and Therapies for Vascular Anomalies.
Queisser A, Seront E, Boon LM, Vikkula M. Queisser A, et al. Circ Res. 2021 Jun 25;129(1):155-173. doi: 10.1161/CIRCRESAHA.121.318145. Epub 2021 Jun 24. Circ Res. 2021. PMID: 34166070 Free article. Review.
Vascular and lymphatic malformations represent a challenge for clinicians. The identification of inherited and somatic mutations in important signaling pathways, including the PI3K (phosphoinositide 3-kinase)/AKT (protein kinase B)/mTOR (mammalian target of rapamycin), RAS …
Vascular and lymphatic malformations represent a challenge for clinicians. The identification of inherited and somatic mutations in i …
Normalization of the vasculature for treatment of cancer and other diseases.
Goel S, Duda DG, Xu L, Munn LL, Boucher Y, Fukumura D, Jain RK. Goel S, et al. Physiol Rev. 2011 Jul;91(3):1071-121. doi: 10.1152/physrev.00038.2010. Physiol Rev. 2011. PMID: 21742796 Free PMC article. Review.
New vessel formation (angiogenesis) is an essential physiological process for embryologic development, normal growth, and tissue repair. ...The imbalance of pro- and anti-angiogenic signaling within tumors creates an abnormal vascular network that is characterized b …
New vessel formation (angiogenesis) is an essential physiological process for embryologic development, normal growth, and tissue repa …
Plastic Bronchitis.
Rubin BK. Rubin BK. Clin Chest Med. 2016 Sep;37(3):405-8. doi: 10.1016/j.ccm.2016.04.003. Epub 2016 Jun 15. Clin Chest Med. 2016. PMID: 27514587 Review.
Current research directions in plastic bronchitis research include understanding the genetics of lymphatic development and maldevelopment, determining how abnormal lymphatic malformations contribute to cast formation, and developing new treatments....
Current research directions in plastic bronchitis research include understanding the genetics of lymphatic development and maldevelop …
Lymphatic malformations.
Smith RJ. Smith RJ. Lymphat Res Biol. 2004;2(1):25-31. doi: 10.1089/1539685041690436. Lymphat Res Biol. 2004. PMID: 15609924 Review.
Lymphatic malformations are rare forms of vascular anomalies. They are most frequently diagnosed at birth and most often occur in the head and neck area. Their treatment continues to be challenging, and treatment methods continue to evolve. In this article, the embryology …
Lymphatic malformations are rare forms of vascular anomalies. They are most frequently diagnosed at birth and most often occur in the …
Morphology and Function of the Lymphatic Vasculature in Patients With a Fontan Circulation.
Mohanakumar S, Telinius N, Kelly B, Lauridsen H, Boedtkjer D, Pedersen M, de Leval M, Hjortdal V. Mohanakumar S, et al. Circ Cardiovasc Imaging. 2019 Apr;12(4):e008074. doi: 10.1161/CIRCIMAGING.118.008074. Circ Cardiovasc Imaging. 2019. PMID: 30943769
Velocity by which the lymph is moved and refill time after manual emptying of the lymphatic vessels showed no differences between the 2 groups. The thoracic duct was elongated 10% ( P=0.0409) and with an abnormal course in the Fontan patients compared with no …
Velocity by which the lymph is moved and refill time after manual emptying of the lymphatic vessels showed no differences betw …
Reengineering the Tumor Vasculature: Improving Drug Delivery and Efficacy.
Stylianopoulos T, Munn LL, Jain RK. Stylianopoulos T, et al. Trends Cancer. 2018 Apr;4(4):258-259. doi: 10.1016/j.trecan.2018.02.010. Epub 2018 Mar 17. Trends Cancer. 2018. PMID: 29606306 Free PMC article. Review.
A solid tumor is like an aberrant organ - comprised of cancer cells and a variety of host cells embedded in an extracellular matrix - nourished by blood vessels and drained by lymphatic vessels. In its journey from the blood stream to cancer cells, a therapeu …
A solid tumor is like an aberrant organ - comprised of cancer cells and a variety of host cells embedded in an extracellular matrix - nouris …
Parallels of Resistance between Angiogenesis and Lymphangiogenesis Inhibition in Cancer Therapy.
Jones D. Jones D. Cells. 2020 Mar 20;9(3):762. doi: 10.3390/cells9030762. Cells. 2020. PMID: 32244922 Free PMC article. Review.
Metastasis is the primary cause of cancer-related mortality. Cancer cells primarily metastasize via blood and lymphatic vessels to colonize lymph nodes and distant organs, leading to worse prognosis. ...Therapies designed to improve lymphatic vessel fu …
Metastasis is the primary cause of cancer-related mortality. Cancer cells primarily metastasize via blood and lymphatic vessels …
Development of Molecular Therapies for Venous Malformations.
Kangas J, Nätynki M, Eklund L. Kangas J, et al. Basic Clin Pharmacol Toxicol. 2018 Sep;123 Suppl 5:6-19. doi: 10.1111/bcpt.13027. Epub 2018 May 29. Basic Clin Pharmacol Toxicol. 2018. PMID: 29668117 Free article. Review.
Vascular anomalies are localized defects of morphogenesis that can affect lymphatic and blood vessels. They are generally called birthmarks, typically observed soon after birth and occurring in up to 10% of children. Based on their clinical and histological c …
Vascular anomalies are localized defects of morphogenesis that can affect lymphatic and blood vessels. They are generally call …
Beyond a Passive Conduit: Implications of Lymphatic Biology for Kidney Diseases.
Jafree DJ, Long DA. Jafree DJ, et al. J Am Soc Nephrol. 2020 Jun;31(6):1178-1190. doi: 10.1681/ASN.2019121320. Epub 2020 Apr 15. J Am Soc Nephrol. 2020. PMID: 32295825 Free PMC article. Review.
The kidney contains a network of lymphatic vessels that clear fluid, small molecules, and cells from the renal interstitium. Through modulating immune responses and via crosstalk with surrounding renal cells, lymphatic vessels have been implicated in t …
The kidney contains a network of lymphatic vessels that clear fluid, small molecules, and cells from the renal interstitium. T …
Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity.
Martin JD, Fukumura D, Duda DG, Boucher Y, Jain RK. Martin JD, et al. Cold Spring Harb Perspect Med. 2016 Dec 1;6(12):a027094. doi: 10.1101/cshperspect.a027094. Cold Spring Harb Perspect Med. 2016. PMID: 27663981 Free PMC article. Review.
Solid tumors consist of cancer cells and stromal cells, including resident and transiting immune cells-all ensconced in an extracellular matrix (ECM)-nourished by blood vessels and drained by lymphatic vessels. The microenvironment constituents are abnorma …
Solid tumors consist of cancer cells and stromal cells, including resident and transiting immune cells-all ensconced in an extracellular mat …
106 results