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51 results

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Page 1
Sulfonylureas and platelet function.
Klaff LJ, Kernoff L, Vinik AI, Jackson WP, Jacobs P. Klaff LJ, et al. Am J Med. 1981 Mar;70(3):627-30. doi: 10.1016/0002-9343(81)90585-4. Am J Med. 1981. PMID: 6782875 Review.
The platelets of many patients with diabetes mellitus are abnormally sensitive to the effects of aggregatory agents in vitro. It has been proposed that this abnormal platelet function may play a role in the pathogenesis of vascular disease in diabetic subject …
The platelets of many patients with diabetes mellitus are abnormally sensitive to the effects of aggregatory agents in vitro. It has been pr …
von Willebrand disease.
Zimmerman TS, Ruggeri ZM. Zimmerman TS, et al. Hum Pathol. 1987 Feb;18(2):140-52. doi: 10.1016/s0046-8177(87)80332-5. Hum Pathol. 1987. PMID: 3100416 Review.
von Willebrand disease (vWD) is a bleeding disorder characterized by a complex hemostatic defect. Abnormal platelet function, usually reflected by a prolonged bleeding time, is the result of a quantitative or qualitative defect of von Willebrand factor (vWF). …
von Willebrand disease (vWD) is a bleeding disorder characterized by a complex hemostatic defect. Abnormal platelet functio …
RASopathies and hemostatic abnormalities: key role of platelet dysfunction.
Di Candia F, Marchetti V, Cirillo F, Di Minno A, Rosano C, Pagano S, Siano MA, Falco M, Assunto A, Boccia G, Magliacane G, Pinna V, De Luca A, Tartaglia M, Di Minno G, Strisciuglio P, Melis D. Di Candia F, et al. Orphanet J Rare Dis. 2021 Dec 2;16(1):499. doi: 10.1186/s13023-021-02122-7. Orphanet J Rare Dis. 2021. PMID: 34857025 Free PMC article.
Splenomegaly is frequently detected and might be a suggestive sign for qualitative platelet dysfunction. A comprehensive clinical assessment should be carried out at diagnosis, during the follow-up and before any surgical procedures. ...
Splenomegaly is frequently detected and might be a suggestive sign for qualitative platelet dysfunction. A comprehensive clinical ass …
Platelet activation in heart failure.
Schäfer A, Eigenthaler M, Bauersachs J. Schäfer A, et al. Clin Lab. 2004;50(9-10):559-66. Clin Lab. 2004. PMID: 15481631 Review.
This review article summarizes the historical knowledge of abnormal platelet function in heart failure, focuses on pathophysiological changes in heart failure which could influence platelet activation, and discusses drug regimens investigated in heart failure …
This review article summarizes the historical knowledge of abnormal platelet function in heart failure, focuses on path …
Importance of platelet aggregation in patients with end-stage renal disease.
Martinović Z, Basić-Jukić N, Pavlović DB, Kes P. Martinović Z, et al. Acta Clin Croat. 2013 Dec;52(4):472-7. Acta Clin Croat. 2013. PMID: 24696998 Review.
The exact etiology of the conflicting hemostatic disorder in the advanced stage of chronic renal disease, i.e. prothrombotic versus bleeding tendency, is not completely understood. Abnormal platelet function in patients with renal failure is not caused by hig …
The exact etiology of the conflicting hemostatic disorder in the advanced stage of chronic renal disease, i.e. prothrombotic versus bleeding …
Aggregation and activation of blood platelets in exercise and training.
El-Sayed MS, Ali N, El-Sayed Ali Z. El-Sayed MS, et al. Sports Med. 2005;35(1):11-22. doi: 10.2165/00007256-200535010-00002. Sports Med. 2005. PMID: 15651910 Review.
Although platelets are important in normal haemostasis, recent evidence emphasises the pivotal role of abnormal platelet function in acute coronary artery diseases, myocardial infarction, unstable angina and stroke. ...
Although platelets are important in normal haemostasis, recent evidence emphasises the pivotal role of abnormal platelet fu …
Hematologic toxicity of sodium valproate.
Acharya S, Bussel JB. Acharya S, et al. J Pediatr Hematol Oncol. 2000 Jan-Feb;22(1):62-5. doi: 10.1097/00043426-200001000-00012. J Pediatr Hematol Oncol. 2000. PMID: 10695824 Review.
Occasional fatal bone marrow failure, myelodysplasia, and a clinical picture resembling acute promyelocytic leukemia have also been seen. ...A bleeding diathesis associated with valproate use may include thrombocytopenia, abnormal platelet function, an …
Occasional fatal bone marrow failure, myelodysplasia, and a clinical picture resembling acute promyelocytic leukemia have also been s …
Aspirin Cessation Before Interventional Procedures: Not Blindly Following Guidelines but Making Test-based Decisions.
Seo KH, Nahm FS, Han WK, Gil HY, Kim JE, Choi EJ, Lee PB. Seo KH, et al. Pain Physician. 2022 Sep;25(6):501-507. Pain Physician. 2022. PMID: 36122261 Free article.
The patients were categorized into either an aspirin-taking or nonaspirin-taking group (Group A or Group N, respectively). The proportion of patients who showed normal/abnormal platelet function was calculated and compared between the groups. ...In Group A, 5 …
The patients were categorized into either an aspirin-taking or nonaspirin-taking group (Group A or Group N, respectively). The proportion of …
Platelet function tests in disease.
Tschopp TB, Zucker MB. Tschopp TB, et al. Annu Rev Med. 1973;24:1-18. doi: 10.1146/annurev.me.24.020173.000245. Annu Rev Med. 1973. PMID: 4575852 Review.
Abnormal platelet function may result from congenital or acquired disturbances in the platelets themselves or their plasma milieu in patients with hemorrhage or thrombosis. ...
Abnormal platelet function may result from congenital or acquired disturbances in the platelets themselves or their pla …
The application of point-of-care platelet function assay in guiding platelet transfusion in aspirin-users with intracranial haemorrhages.
Cheng KY, Tsang CP, Leung GKK, Lui WM. Cheng KY, et al. J Clin Neurosci. 2018 Sep;55:52-56. doi: 10.1016/j.jocn.2018.06.037. Epub 2018 Jul 2. J Clin Neurosci. 2018. PMID: 30042067
Overall, eight (40%) patients were 'early and persistent transfusion responders', five 'delayed transfusion responders', and five (25%) had persistently abnormal platelet function. Two (10%) patients who initially responded to transfusion failed to maintain n …
Overall, eight (40%) patients were 'early and persistent transfusion responders', five 'delayed transfusion responders', and five (25%) had …
51 results