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Quoted phrase not found in phrase index: "Abnormal thymus morphology"
Page 1
Thymomas.
LeGolvan DP, Abell MR. LeGolvan DP, et al. Cancer. 1977 May;39(5):2142-57. doi: 10.1002/1097-0142(197705)39:5<2142::aid-cncr2820390531>3.0.co;2-q. Cancer. 1977. PMID: 558046
The most common presenting symptoms were related to myasthenia gravis, and symptoms due to pressure on mediastinal structures were next in frequency. Other endocrine abnormalities were present in 20% of patients. Two male patients also had carcinomas of the thyroid glan …
The most common presenting symptoms were related to myasthenia gravis, and symptoms due to pressure on mediastinal structures were next in f …
Obesity-induced thymic involution and cancer risk.
Lagou MK, Karagiannis GS. Lagou MK, et al. Semin Cancer Biol. 2023 Aug;93:3-19. doi: 10.1016/j.semcancer.2023.04.008. Epub 2023 Apr 22. Semin Cancer Biol. 2023. PMID: 37088128 Free article. Review.
A key mechanism underlying such increased cancer risk is the thymus-dependent debilitation of adaptive immunity, which is responsible for orchestrating immunoediting mechanisms and tumor immune surveillance. ...The majority of such studies has focused on obesity-driven chr …
A key mechanism underlying such increased cancer risk is the thymus-dependent debilitation of adaptive immunity, which is responsible …
Thymus variants on imaging in patients with rheumatoid arthritis-clinical and immunological significance.
Murata O, Suzuki K, Sugiura H, Kondo Y, Takeshita M, Koga K, Takiguchi M, Kurisu R, Kassai Y, Yasuoka H, Yamaoka K, Morita R, Yoshimura A, Takeuchi T. Murata O, et al. Rheumatology (Oxford). 2021 Dec 1;60(12):5595-5600. doi: 10.1093/rheumatology/keab164. Rheumatology (Oxford). 2021. PMID: 33590850
OBJECTIVES: We sought to clarify the presence of radiographic thymus variants using a scoring system, and their association with clinical and immunological features in RA patients. ...RESULTS: Thymic enlargement was found in 76 (19.6%) patients, and a thym …
OBJECTIVES: We sought to clarify the presence of radiographic thymus variants using a scoring system, and their associa …
Recurrent Tumor Suppressor Alterations in Primary Pericardial Mesothelioma.
Schaefer IM, Mariño-Enríquez A, Hammer MM, Padera RF, Sholl LM. Schaefer IM, et al. Mod Pathol. 2023 Sep;36(9):100237. doi: 10.1016/j.modpat.2023.100237. Epub 2023 Jun 8. Mod Pathol. 2023. PMID: 37295554
Staining for tumor suppressors revealed loss of p16, MTAP, and Merlin (NF2) expression in 2 cases and loss of BAP1 and p53 in 1 case. Abnormal cytoplasmic BAP1 expression was observed in an additional case. Protein expression abnormalities correlated with NGS …
Staining for tumor suppressors revealed loss of p16, MTAP, and Merlin (NF2) expression in 2 cases and loss of BAP1 and p53 in 1 case. Abn …
A TP63 mutation identified in a Han Chinese family with ectodermal dysplasia.
Zhou X, Zhang C, Fan L, Wu S, Yao S, Wang L, Zhong W, Ma L, Pan Y. Zhou X, et al. Arch Oral Biol. 2023 Aug;152:105731. doi: 10.1016/j.archoralbio.2023.105731. Epub 2023 May 18. Arch Oral Biol. 2023. PMID: 37257258
RESULTS: A heterozygous missense variant at TP63 exon 8 (c.1010 G>A:p.Arg337Gln) was identified in the proband. This variant was predicted deleterious and likely to impair the local stability of the protein. ...Furthermore, spatial transcriptome data of mice embryos sho …
RESULTS: A heterozygous missense variant at TP63 exon 8 (c.1010 G>A:p.Arg337Gln) was identified in the proband. This variant was predi …
Sella turcica morphology and the pituitary gland-a new contribution to craniofacial diagnostics based on histology and neuroradiology.
Kjær I. Kjær I. Eur J Orthod. 2015 Feb;37(1):28-36. doi: 10.1093/ejo/cjs091. Epub 2012 Nov 16. Eur J Orthod. 2015. PMID: 23159420 Review.
Similarities between prenatal and postnatal deviations in sella turcica morphology were demonstrated. Malformations in the pituitary gland were observed in several cases. ...Deviations in the anterior wall seem to be associated with deviations specifically in …
Similarities between prenatal and postnatal deviations in sella turcica morphology were demonstrated. Malformations in the pituitary …
Correlation of first-trimester thymus size with chromosomal anomalies.
Kleemann S, Koch R, Schmitz R, Köster HA, Braun J, Steinhard J, Oelmeier K, Klockenbusch W, Möllers M. Kleemann S, et al. J Perinat Med. 2021 Feb 10;49(5):604-613. doi: 10.1515/jpm-2020-0599. Print 2021 Jun 25. J Perinat Med. 2021. PMID: 33561911
The included cases were subdivided into six groups: (1) trisomy 21, (2) trisomy 18, (3) trisomy 13, (4) Turner syndrome, (5) triploidy and (6) normal controls. Thymus size measurements were adjusted to the week of gestation, which was determined by ultrasound using crown-r …
The included cases were subdivided into six groups: (1) trisomy 21, (2) trisomy 18, (3) trisomy 13, (4) Turner syndrome, (5) triploidy and ( …
Thymic abnormalities and autoimmune diseases.
Tsuchiya M, Asakura H, Yoshimatsu H. Tsuchiya M, et al. Keio J Med. 1989 Dec;38(4):383-402. doi: 10.2302/kjm.38.383. Keio J Med. 1989. PMID: 2698424 Free article. Review.
The supernatant of thymus epithelial cell culture (STEC) has the capability of differentiating human bone marrow cells and of facilitating disease-specific immune abnormalities. ...From these observations, it is thought to be important to investigate the immu …
The supernatant of thymus epithelial cell culture (STEC) has the capability of differentiating human bone marrow cells and of facilit …
Defects of immunoregulatory mechanisms in myasthenia gravis: role of IL-17.
Gradolatto A, Nazzal D, Foti M, Bismuth J, Truffault F, Le Panse R, Berrih-Aknin S. Gradolatto A, et al. Ann N Y Acad Sci. 2012 Dec;1274:40-7. doi: 10.1111/j.1749-6632.2012.06791.x. Ann N Y Acad Sci. 2012. PMID: 23252896 Review.
Deficient immunoregulation is consistently observed in autoimmune diseases. Here, we summarize the abnormalities of the T cell response in autoimmune myasthenia gravis (MG) by focusing on activation markers, inflammatory features, and imbalance between the different …
Deficient immunoregulation is consistently observed in autoimmune diseases. Here, we summarize the abnormalities of the T cell …
Myasthenia gravis: a comprehensive review of immune dysregulation and etiological mechanisms.
Berrih-Aknin S, Le Panse R. Berrih-Aknin S, et al. J Autoimmun. 2014 Aug;52:90-100. doi: 10.1016/j.jaut.2013.12.011. Epub 2014 Jan 3. J Autoimmun. 2014. PMID: 24389034 Review.
This review summarizes the clinical and biological data available for different subgroups of patients, who are classified according to antigenic target, age of onset, and observed thymic abnormalities, such as follicular hyperplasia or thymoma. Here, we analyze in d …
This review summarizes the clinical and biological data available for different subgroups of patients, who are classified according to antig …
241 results