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Case Report: X-Linked SASH3 Deficiency Presenting as a Common Variable Immunodeficiency.
Labrador-Horrillo M, Franco-Jarava C, Garcia-Prat M, Parra-Martínez A, Antolín M, Salgado-Perandrés S, Aguiló-Cucurull A, Martinez-Gallo M, Colobran R. Labrador-Horrillo M, et al. Front Immunol. 2022 Apr 8;13:881206. doi: 10.3389/fimmu.2022.881206. eCollection 2022. Front Immunol. 2022. PMID: 35464398 Free PMC article.
The patient's immunological phenotype included marked B cell lymphopenia with reduced pre-switch and switch memory B cells, decreased CD4(+) and CD8(+) naive T cells, elevated CD4(+) and CD8(+) T(EMRA) cells, and abnormal T cell activation and prolifer …
The patient's immunological phenotype included marked B cell lymphopenia with reduced pre-switch and switch memory B cells, decreased CD4(+) …
Association between NKG2/KLR gene variants and epilepsy in Autism Spectrum Disorder.
Kaminski VL, Kulmann-Leal B, Tyska-Nunes GL, Beltrame BP, Riesgo RDS, Schüler-Faccini L, Roman T, Schuch JB, Chies JAB. Kaminski VL, et al. J Neuroimmunol. 2023 Aug 15;381:578132. doi: 10.1016/j.jneuroim.2023.578132. Epub 2023 Jun 16. J Neuroimmunol. 2023. PMID: 37352688
Several lines of evidence indicate that alterations of the immune system account for ASD development, including the presence of brain-reactive antibodies, abnormal T cell activation, altered cytokine levels in brain, cerebrospinal fluid and peripheral …
Several lines of evidence indicate that alterations of the immune system account for ASD development, including the presence of brain-reacti …
Malignancy associated hemophagocytic lymphohistiocytosis in children.
Singh A, Dawman L, Seth R. Singh A, et al. J Cancer Res Ther. 2018 Apr-Jun;14(3):559-562. doi: 10.4103/0973-1482.188437. J Cancer Res Ther. 2018. PMID: 29893316 Free article.
AIM OF STUDY: Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder of immune dysregulation resulting in abnormal T-cell activation and inflammatory cytokine production which produces a constellation of clinical features unique to HLH. ...
AIM OF STUDY: Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder of immune dysregulation resulting in abnormal T-c …
Comparison of T-cell receptor diversity of people with myalgic encephalomyelitis versus controls.
Dibble JJ, Ferneyhough B, Roddis M, Millington S, Fischer MD, Parkinson NJ, Ponting CP. Dibble JJ, et al. BMC Res Notes. 2024 Jan 4;17(1):17. doi: 10.1186/s13104-023-06616-4. BMC Res Notes. 2024. PMID: 38178251 Free PMC article.
Its frequent onset after infection suggests autoimmune involvement or that it arises from abnormal T-cell activation. RESULTS: To test this hypothesis, we sequenced the genomic loci of alpha/delta, beta and gamma T-cell receptors (TCR) from 40 human bl …
Its frequent onset after infection suggests autoimmune involvement or that it arises from abnormal T-cell activation …
Nephrotic syndrome associated with hemophagocytic syndrome.
Thaunat O, Delahousse M, Fakhouri F, Martinez F, Stephan JL, Noël LH, Karras A. Thaunat O, et al. Kidney Int. 2006 May;69(10):1892-8. doi: 10.1038/sj.ki.5000352. Kidney Int. 2006. PMID: 16557222 Free article.
Nephrotic syndrome should be included among the renal complications of HPS with acute renal failure. We postulate that abnormal T-cell activation and/or high pro-inflammatory cytokine levels during HPS might cause podocyte injuries, especially among Af …
Nephrotic syndrome should be included among the renal complications of HPS with acute renal failure. We postulate that abnormal T …
Increased alkaline phosphatase isoforms in autoimmune diseases.
Hanna AN, Waldman WJ, Lott JA, Koesters SC, Hughes AM, Thornton DJ. Hanna AN, et al. Clin Chem. 1997 Aug;43(8 Pt 1):1357-64. Clin Chem. 1997. PMID: 9267314
ALP-10 is a sensitive but nonspecific marker of an active autoimmune process and appears to have the ability to detect abnormal T-cell activation. ALP-10 may be a useful test in the screening for autoimmune disorders....
ALP-10 is a sensitive but nonspecific marker of an active autoimmune process and appears to have the ability to detect abnormal T …
Hemophagocytic Lymphohistiocytosis Associated With 2 Cases of Pediatric Lymphocyte-depleted Classic Hodgkin Lymphoma.
Cader FZ, Colmenero I, Mussai F. Cader FZ, et al. J Pediatr Hematol Oncol. 2019 Jul;41(5):e341-e345. doi: 10.1097/MPH.0000000000001398. J Pediatr Hematol Oncol. 2019. PMID: 30601404
Hemophagocytic lymphohistiocytosis (HLH) is a rare and often fatal syndrome of abnormal T-cell activation and cytokine production, which can be familial or secondary in nature. ...
Hemophagocytic lymphohistiocytosis (HLH) is a rare and often fatal syndrome of abnormal T-cell activation and cy …